Evidence map›Paper›PMID 36578785›Full record

ReviewFrontiers in cell and developmental biology2022

Contribution of integrin adhesion to cytokinetic abscission and genomic integrity.

Bhavna Rani, Deepesh K Gupta, Staffan Johansson, Siamak A Kamranvar

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Bhavna RaniDepartment of Medical Biochemistry and Microbiology (IMBIM), Biomedical Center, Uppsala University, Uppsala, Sweden.
Deepesh K GuptaDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Staffan JohanssonDepartment of Medical Biochemistry and Microbiology (IMBIM), Biomedical Center, Uppsala University, Uppsala, Sweden.
Siamak A KamranvarDepartment of Medical Biochemistry and Microbiology (IMBIM), Biomedical Center, Uppsala University, Uppsala, Sweden.
Uppsala University · SEWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent research shows that integrin-mediated adhesion contributes to the regulation of cell division at two key steps: the formation of the mitotic spindle at the mitotic entry and the final cytokinetic abscission at the mitotic exit. Failure in either of these processes will have a direct impact on the other in each round of the cell cycle and on the genomic integrity. This review aims to present how integrin signals are involved at these cell cycle stages under normal conditions and some safety mechanisms that may counteract the generation of aneuploid cells in cases of defective integrin signals.

Indexed as

abscissioncentrosomegenome integrityintegrinmitosis

Identifiers

PMID36578785
PMCPMC9791049
OpenAlexW4312122562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.