Evidence map›Paper›PMID 36578696›Full record

ArticleSurgery open science2023

Adverse financial and clinical burden of the use of prophylactic antibiotics in neurosurgical patients.

Naairah Khan, Zairah Shamshad, Holly Batchelor-Parry, Iqra Marriyam, Sayed Samed Talibi, Rahim A Hussain

Abstract read
In one paragraph

Article in Surgery open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naairah KhanUniversity Hospitals Coventry and Warwickshire NHS trust, United Kingdom.
Zairah ShamshadUniversity Hospitals Coventry and Warwickshire NHS trust, United Kingdom.
Holly Batchelor-ParryUniversity Hospitals Coventry and Warwickshire NHS trust, United Kingdom.
Iqra MarriyamUniversity Hospitals Coventry and Warwickshire NHS trust, United Kingdom.
Sayed Samed TalibiUniversity Hospitals Coventry and Warwickshire NHS trust, United Kingdom.
Rahim A HussainUniversity Hospitals Coventry and Warwickshire NHS trust, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current guidance does not support the administration of prophylactic antibiotics in non-infected post-operative surgical cases including neurosurgery. Materials and methods: This paper is a qualitative assessment, highlighting the economic cost of excessive antimicrobial prescription and the healthcare costs of the extra days of admission in hospital. Results: One hundred and one neurosurgical cases were analysed in a single institution over a one-year period. The additional course of post-operative antibiotics has a cost of £56.72 and receiving prolonged post-operative antibiotics added on average £1121.10 to their admission bill. Up to 13.4 patients may have experienced an adverse drug event. Conclusion: This paper reinforces the adherence to guidelines can aid in the reduction of adverse drug events, improve patient outcomes, and reduce costs associated with unnecessary drug prescriptions and administration.

Indexed as

AntibioticsNeurosurgeryOveruseProphylaxisResistanceSARS-COVID-19, Severe acute respiratory syndrome coronavirus disease 2019

Identifiers

PMID36578696
PMCPMC9791924

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.