Evidence map›Paper›PMID 36578672›Full record

ArticleToxicology reports2023

Experimental evidence of a limited impact of new-generation perfluoroalkyl substance C6O4 on differentiating human dopaminergic neurons from induced pluripotent stem cells.

Andrea Di Nisio, Marta Trevisan, Stefano Dall'Acqua, Micaela Pannella, Claudia Pappalardo, Alberto Ferlin, Carlo Foresta, Luca De Toni

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andrea Di NisioDepartment of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Padova, Italy.
Marta TrevisanDepartment of Molecular Medicine, University of Padova, Padova, Italy.
Stefano Dall'AcquaDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Micaela PannellaIRCSS Istituto Ortopedico Rizzoli, Bologna, Italy.
Claudia PappalardoDepartment of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Padova, Italy.
Alberto FerlinDepartment of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Padova, Italy.
Carlo ForestaDepartment of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Padova, Italy.
Luca De ToniDepartment of Medicine, Unit of Andrology and Reproductive Medicine, University of Padova, Padova, Italy.
University of Padua · ITIstituto Ortopedico Rizzoli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perfluoroalkyl substances (PFASs) are persistent pollutants, raising concerns for human health. Legacy PFAS perfluoro-octanoic acid (PFOA) accumulate in brains of people at high environmental exposure, especially in areas enriched with dopaminergic neurons (DN).

Indexed as

Dopaminergic neuronEndocrine disruptorsHuman induced pluripotent stem cellsPerfluoroalkyl substancesTyrosine hydroxylase

Identifiers

PMID36578672
PMCPMC9791692
OpenAlexW4311230639

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.