ArticleProceedings (Baylor University. Medical Center)2023
COVID-19 vaccination-related hemophagocytic lymphohistiocytosis presenting as acute liver failure.
Article in Proceedings (Baylor University. Medical Center), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Acute liver failure in a patient with recent coronavirus disease 2019 infection requiring liver transplantation: a case report.Journal of medical case reports · 2026Article
- Probable secondary hemophagocytic lymphohistiocytosis manifesting as central nervous system lesions after COVID-19 vaccination: a case report.Frontiers in neurology · 2024Article
- COVID-19 Outcomes in Inflammatory Bowel Disease Hospitalized Patients: A Comprehensive Analysis Using the National Inpatient Sample.Gastroenterology research · 2023Article
- Acute Liver Failure Caused by Secondary Hemophagocytic Lymphohistiocytosis After COVID-19 Vaccination - Case Report and Literature Review.International medical case reports journal · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
Acute liver failure following COVID-19 infection and/or vaccination is very rare and can be secondary to hemophagocytic lymphohistiocytosis (HLH). Liver injury in such cases appears to be extrinsic and thus treatment hinges on prompt diagnosis and reversal of the primary disease. We describe a patient who developed acute liver failure secondary to HLH after receiving a second dose of the Pfizer COVID-19 vaccine. Persistently elevated liver function tests, fevers, and cytopenia following COVID-19 vaccination should prompt clinicians to calculate an H-score to evaluate for the presence of HLH.
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