Evidence map›Paper›PMID 36578574›Full record

ArticleFrontiers in microbiology2022

Specific DNAzymes cleave the 300-618 nt of 5'UTR to inhibit DHAV-1 translation and replication.

Yanglin Li, Ling Wei, Anchun Cheng, Mingshu Wang, Xumin Ou, Sai Mao, Bin Tian, Qiao Yang, Ying Wu, Shaqiu Zhang and 11 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Yanglin LiInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ling WeiInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Anchun ChengInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Mingshu WangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xumin OuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Sai MaoInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Bin TianInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qiao YangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ying WuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shaqiu ZhangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Juan HuangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qun GaoInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Di SunInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xinxin ZhaoInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Renyong JiaInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Mafeng LiuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Dekang ZhuKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, China.
Shun ChenInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yanling YuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ling ZhangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Leichang PanInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNAzymes effectively inhibit the expression of viral genes. Duck hepatitis A virus type-1 (DHAV-1) genomic RNA carries an internal ribosome entry site (IRES). The IRES initiates the translation of DHAV-1

Indexed as

cleavageDNAzymeduck hepatitis A virus type 1DZ454inhibitionthe 300–618 nt of 5′UTR

Identifiers

PMID36578574
PMCPMC9791187
OpenAlexW4311403451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.