Evidence map›Paper›PMID 36578488›Full record

ArticleFrontiers in immunology2022

Potentiating pneumococcal glycoconjugate vaccine PCV13 with saponin adjuvant VSA-1.

Hyunjung Kim, Jigui Yu, Di Bai, Moon H Nahm, Pengfei Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Genome sequences of 36Microbiology resource announcements · 2024
    Article
  4. Development of semisynthetic saponin immunostimulants.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyunjung KimDepartment of Chemistry, University of Alabama at Birmingham, Birmingham, AL, United States.
Jigui YuDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Di BaiDepartment of Chemistry, University of Alabama at Birmingham, Birmingham, AL, United States.
Moon H NahmDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Pengfei WangDepartment of Chemistry, University of Alabama at Birmingham, Birmingham, AL, United States.
University of Alabama at Birmingham · US

Funding

Development of Structurally Defined Synthetic Vaccine Adjuvants-equip supR01GM120159 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, PENGFEI · 2017 to 2020
$1.2M
NIGMS NIH HHS R01 GM120159World Health Organization 001
6 · The paper itself

Abstract

VSA-1 is a semisynthetic saponin adjuvant prepared from naturally occurring

Indexed as

Pneumococcal VaccinesSaponinsAdjuvants, ImmunologicAdjuvants, PharmaceuticAnimalsFemaleImmunoglobulin GMiceAdjuvants, ImmunologicAdjuvants, PharmaceuticImmunoglobulin GPneumococcal VaccinesSaponinsadjuvantimmunostimulantMomordica saponinpneumococcal vaccineVSA-1

Identifiers

PMID36578488
PMCPMC9790987
OpenAlexW4311127548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.