Evidence map›Paper›PMID 36578045›Full record

ArticleNutrition & metabolism2022

Ginger supplement significantly reduced length of hospital stay in individuals with COVID-19.

Yaqi Li, Dawei Yang, Xiwen Gao, Minjie Ju, Hao Fang, Zuoqin Yan, Huanru Qu, Yuanhao Zhang, Linshan Xie, Huifen Weng and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nutrition & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Yaqi Li *Department of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Fudan University, Shanghai, China.
Dawei Yang *Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiwen Gao *Department of Pulmonary and Critical Care Medicine, Minhang Hospital, Fudan University, Shanghai, China.
Minjie JuDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Hao FangDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Zuoqin YanZhongshan Hospital, Fudan University, Shanghai, China.
Huanru QuDepartment of Rheumatology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yuanhao ZhangHuashan Hospital, Fudan University, Shanghai, China.
Linshan XieDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Huifen WengShanghai Suvalue Healthcare Scientific Co., Ltd., Shanghai, China.
Chunxue BaiDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Yuanlin SongDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhirong SunDepartment of Anesthesiology, Fudan University Shanghai Cancer Center, Shanghai, China. sunrongsun@aliyun.com.
Wenye GengFudan Zhangjiang Institute, Fudan University, Shanghai, China. drug@fudan.edu.cn.
Xiang GaoDepartment of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Fudan University, Shanghai, China. Xiang_Gao@fudan.edu.cn.
Fudan University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNFudan University Shanghai Cancer Center · CNMinhang District Central Hospital · CNShanghai Institute of Hematology · CNShanghai University of Traditional Chinese Medicine · CNSun Yat-sen University · CN

Funding

hanghai Municipal Science and Technology Major Project ZD2021CY001National Natural Science Foundation of China 81971863National Natural Science Foundation of China 82170110Science and Technology Commission of Shanghai Municipality 20DZ2261200Shanghai Municipal Key Clinical Specialty shslczdzk02201Shanghai Natural Science Foundation 22ZR1444700Shanghai Pujiang Program 20PJ1402400
6 · The paper itself

Abstract

backgroundEvidence from previous studies has suggested that ginger extract exhibits the potential as an alternative treatment for Coronavirus disease 2019 (COVID-19). Here, we want to investigate whether ginger supplement improves the clinical manifestation of hospitalized COVID-19 individuals.

methodsA total of 227 hospitalized individuals with COVID-19 were randomized to either the control (n = 132) or intervention group (n = 95). The intervention group took ginger supplement orally at the dosage of 1.5 g twice daily, until they were discharged from the hospital. Both groups received the same standard of general medical care during hospitalization, and the length of stay was recorded and compared between groups.

resultsAmong all participants, a significant reduction in hospitalization time (the difference between the treatment and control groups was 2.4 d, 95% CI 1.6-3.2) was detected in response to the ginger supplement. This effect was more pronounced in men, participants aged 60 years or older, and participants with pre-existing medical conditions, relative to their counterparts (P-interactions < 0.05 for all).

conclusionGinger supplement significantly shortened the length of stay of hospitalized individuals with COVID-19.

trial registrationThe trial was registered on the Chinese Clinical Trial Registry (ChiCTR2200059824).

Indexed as

COVID-19GingerHospital length of stayRandomized control trial

Identifiers

PMID36578045
PMCPMC9795954
OpenAlexW4313313067

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.