Evidence map›Paper›PMID 36577987›Full record

ArticleBMC ophthalmology2022

Detecting eyes with high risk of angle closure among apparently normal eyes by anterior segment OCT: a health examination center-based model.

Sigeng Lin, Ying Hu, Cong Ye, Nathan Congdon, Ruirong You, Shanshan Liu, Chi Liu, Fan Lv, Shaodan Zhang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Sigeng LinThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, No.270 Xueyuanxi Street, Lucheng District, Wenzhou, 325027, Zhejiang, China.
Ying HuDepartment of Ophthalmology, The Forth People's Hospital of Shenyang, Huanggu District, NO. 20 Huanghenan Street, Shenyang, 110031, Liaoning, China.
Cong YeThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, No.270 Xueyuanxi Street, Lucheng District, Wenzhou, 325027, Zhejiang, China.
Nathan CongdonCentre for Public Health, Queen's University Belfast, Belfast, UK.
Ruirong YouThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, No.270 Xueyuanxi Street, Lucheng District, Wenzhou, 325027, Zhejiang, China.
Shanshan LiuDepartment of Ophthalmology, The Forth People's Hospital of Shenyang, Huanggu District, NO. 20 Huanghenan Street, Shenyang, 110031, Liaoning, China.
Chi LiuDepartment of Ophthalmology, The Forth People's Hospital of Shenyang, Huanggu District, NO. 20 Huanghenan Street, Shenyang, 110031, Liaoning, China. Liuchi812@126.com.
Fan LvThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, No.270 Xueyuanxi Street, Lucheng District, Wenzhou, 325027, Zhejiang, China.
Shaodan ZhangThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, No.270 Xueyuanxi Street, Lucheng District, Wenzhou, 325027, Zhejiang, China. shaodan_zhang@eye.ac.cn.
Wenzhou Medical University · CNAffiliated Eye Hospital of Wenzhou Medical College · CNNational Clinical Research Center for Digestive Diseases · CNSun Yat-sen University · CN

Funding

the Basic Scientific Research Program of Wenzhou Y20190695the Key Innovation and Guidance Program of the Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University YNZD2201903the National Key R&D Program of China 2020YFC2008200the Scientific Research Foundation of the Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University KYQD20180306
6 · The paper itself

Abstract

backgroundThe main barriers keeping individuals with high-risk of angle closure from seeking eye-care service are the absence of both disease awareness and convenient and low-cost access to the ocular health care system. Present study described the efficacy of a health examination center-based screening model designed to detect eyes with high risk of angle closure (HRAC) among healthy individuals using anterior segment optical coherence tomography (AS-OCT).

methodsFrom March 1 to April 30, 2017, consecutive individuals aged ≥ 40 years undergoing routine physical examinations at a health examination center were invited to enroll. Presenting visual acuity (PVA), intraocular pressure (IOP) measurement, non-mydriatic fundus photography and AS-OCT were performed by three trained nurses. Participants with PVA < 6/12 in the better-seeing eye, IOP ≥ 24 mmHg, or abnormal fundus photography in either eye were referred to the outpatient clinic, but not included in the analysis. Eyes with HRAC were defined as having trabecular-iris angle < 12 degrees in ≥ 3 quadrants. Configuration of the iris was classified into flat, bowing, bombe, thick peripheral iris and mixed mechanism.

resultsAltogether, 991 participants (77.3%) with readable OCT images (mean age 55.5 ± 9.0 years; 58.4% men) were included. HRAC was diagnosed in 78 eyes (7.9%, 61.3 ± 8.2 years, 41.0% men). The prevalence of HRAC increased with age (p < 0.001) and was much higher among women (11.2%) than men (5.5%) (p = 0.001). The mixed mechanism iris configuration was most common among eyes with HRAC (37/78, 47.4%).

conclusionHRAC is prevalent among asymptomatic Chinese adults undergoing routine health screening. Health examination center-based eye screening with AS-OCT administered by non-specialists may be a good model to screen narrow angles in the population at large.

Indexed as

Glaucoma, Angle-ClosureTomography, Optical CoherenceAdultAnterior Eye SegmentFemaleGonioscopyHumansIntraocular PressureIrisMaleMiddle AgedAnterior segment OCTHealth examination centerNarrow angleScreening

Identifiers

PMID36577987
PMCPMC9798562
OpenAlexW4313197691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.