Evidence map›Paper›PMID 36577795›Full record

Observational studyPediatric research2023

Structural racism is associated with adverse postnatal outcomes among Black preterm infants.

Kayla L Karvonen, Safyer McKenzie-Sampson, Rebecca J Baer, Laura Jelliffe-Pawlowski, Elizabeth E Rogers, Matthew S Pantell, Brittany D Chambers

Abstract readObservational Study
In one paragraph

Observational study in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Staff perspectives on racial inequities in the neonatal intensive care unit: the REJOICE study.Journal of perinatology : official journal of the California Perinatal Association · 2026
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  16. Impact of race-based customization on detection of fetal growth restriction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kayla L KarvonenDepartment of Pediatrics, University of California San Francisco, San Francisco, CA, USA. kayla.karvonen@ucsf.edu.ORCID 0000-0001-8213-6697
Safyer McKenzie-SampsonCalifornia Preterm Birth Initiative, San Francisco, CA, USA.
Rebecca J BaerCalifornia Preterm Birth Initiative, San Francisco, CA, USA.
Laura Jelliffe-PawlowskiCalifornia Preterm Birth Initiative, San Francisco, CA, USA.
Elizabeth E RogersDepartment of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Matthew S PantellDepartment of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Brittany D ChambersDepartment of Human Ecology, University of California Davis, Davis, CA, USA.

Funding

Transdisciplinary Research Training to Reduce Disparities in Preterm Birth and Improve Maternal and Neonatal OutcomesT32HD098057 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUPPERMANN, MIRIAM · 2019 to 2023
$1.4M
NICHD NIH HHS T32 HD098057
6 · The paper itself

Abstract

backgroundStructural racism contributes to racial disparities in adverse perinatal outcomes. We sought to determine if structural racism is associated with adverse outcomes among Black preterm infants postnatally.

methodsObservational cohort study of 13,321 Black birthing people who delivered preterm (gestational age 22-36 weeks) in California in 2011-2017 using a statewide birth cohort database and the American Community Survey. Racial and income segregation was quantified by the Index of Concentration at the Extremes (ICE) scores. Multivariable generalized estimating equations regression models were fit to test the association between ICE scores and adverse postnatal outcomes: frequent acute care visits, readmissions, and pre- and post-discharge death, adjusting for infant and birthing person characteristics and social factors.

resultsBlack birthing people who delivered preterm in the least privileged ICE tertiles were more likely to have infants who experienced frequent acute care visits (crude risk ratio [cRR] 1.3 95% CI 1.2-1.4), readmissions (cRR 1.1 95% CI 1.0-1.2), and post-discharge death (cRR 1.9 95% CI 1.2-3.1) in their first year compared to those in the privileged tertile. Results did not differ significantly after adjusting for infant or birthing person characteristics.

conclusionStructural racism contributes to adverse outcomes for Black preterm infants after hospital discharge. IMPACT STATEMENT: Structural racism, measured by racial and income segregation, was associated with adverse postnatal outcomes among Black preterm infants including frequent acute care visits, rehospitalizations, and death after hospital discharge. This study extends our understanding of the impact of structural racism on the health of Black preterm infants beyond the perinatal period and provides reinforcement to the concept of structural racism contributing to racial disparities in poor postnatal outcomes for preterm infants. Identifying structural racism as a primary cause of racial disparities in the postnatal period is necessary to prioritize and implement appropriate structural interventions to improve outcomes.

Indexed as

Infant, PrematurePremature BirthAftercareFemaleHumansInfantInfant, NewbornPatient DischargePregnancySystemic RacismWhite

Identifiers

PMID36577795
PMCPMC9795138

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.