Evidence map›Paper›PMID 36577520›Full record

ArticleGenome research2023

Dynamic regulation of gonadal transposon control across the lifespan of the naturally short-lived African turquoise killifish.

Bryan B Teefy, Ari Adler, Alan Xu, Katelyn Hsu, Param Priya Singh, Bérénice A Benayoun

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Engulfment by brain macrophages in a short-lived vertebrate.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bryan B TeefyLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, USA.ORCID 0000-0002-1982-1728
Ari AdlerLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, USA.ORCID 0000-0002-6470-0458
Alan XuLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, USA.ORCID 0000-0002-8698-9301
Katelyn HsuLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, USA.ORCID 0000-0001-9418-301X
Param Priya SinghDepartment of Genetics, Stanford University, Stanford, California 94305, USA.ORCID 0000-0002-3325-8767
Bérénice A BenayounLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, USA.ORCID 0000-0002-7401-4777
University of Southern California · USStanford University · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4M
USC Geroscience Training in the Biology of AgingT32AG052374 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sean P CURRAN · 2016 to 2026
$5.3M
Understanding the regulation and impact of transposable elements in Vertebrate health and diseaseR35GM142395 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BENAYOUN, BERENICE ANATH · 2021 to 2025
$2.2M
Transposable elements as drivers of normal and accelerated aging in VertebratesR21AG063739 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BENAYOUN, BERENICE ANATH · 2019 to 2020
$464k
NCI NIH HHS P30 CA014089NIA NIH HHS R21 AG063739NIA NIH HHS T32 AG052374NIGMS NIH HHS R35 GM142395
6 · The paper itself

Abstract

Although germline cells are considered to be functionally "immortal," both the germline and supporting somatic cells in the gonad within an organism experience aging. With increased age at parenthood, the age-related decline in reproductive success has become an important biological issue for an aging population. However, molecular mechanisms underlying reproductive aging across sexes in vertebrates remain poorly understood. To decipher molecular drivers of vertebrate gonadal aging across sexes, we perform longitudinal characterization of the gonadal transcriptome throughout the lifespan in the naturally short-lived African turquoise killifish (

Indexed as

FundulidaeLongevityAgingAnimalsFemaleGonadsMalePiwi-Interacting RNARNA, Small InterferingPiwi-Interacting RNARNA, Small Interfering

Identifiers

PMID36577520
PMCPMC9977155
OpenAlexW4313280107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.