Evidence map›Paper›PMID 36576946›Full record

ArticleBlood advances2023

Identification of TCF3 germline variants in pediatric B-cell acute lymphoblastic leukemia.

Carolin Escherich, Wenan Chen, Satoshi Miyamoto, Yui Namikawa, Wenjian Yang, David T Teachey, Zhenhua Li, Elizabeth A Raetz, Eric Larsen, Meenakshi Devidas and 8 more

Abstract read
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Genetic influences on haematopoiesis.Nature reviews. Genetics · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Carolin EscherichDepartment for Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany.ORCID 0000-0002-1402-3647
Wenan ChenCenter for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN.
Satoshi MiyamotoDepartment of Pediatrics, Tokyo Medical and Dental University, Tokyo, Japan.
Yui NamikawaDepartment of Pediatrics, Tokyo Medical and Dental University, Tokyo, Japan.
Wenjian YangDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-7305-5649
David T TeacheyDepartment of Pediatrics and Center for Childhood Cancer Research, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-7373-8987
Zhenhua LiDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN.
Elizabeth A RaetzDivision of Pediatric Hematology and Oncology, Perlmutter Cancer Center, New York University Langone Health, New York, NY.
Eric LarsenDepartment of Pediatrics, Maine Children's Cancer Program, Scarborough, ME.
Meenakshi DevidasDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-1099-3478
Paul L MartinPediatric Transplant and Cellular Therapy, Duke University School of Medicine, Durham, NC.
W Paul BowmanDepartment of Pediatrics, Cook Children's Medical Center, Fort Worth, TX.
Gang WuCenter for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN.
Ching-Hon PuiDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0003-0303-5658
Stephen P HungerDepartment of Pediatrics and Center for Childhood Cancer Research, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-5492-3957
Mignon L LohBen Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA.
Masatoshi TakagiDepartment of Pediatrics, Tokyo Medical and Dental University, Tokyo, Japan.
Jun J YangDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Children's Oncology Group Statistics &Data Center GrantU10CA098413 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI DEVIDAS, MEENAKSHI · 2003 to 2013
$67.5M
CPML - Project 3: Genome-wide Studies of Adverse EffectsP50GM115279 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI LOH, MIGNON LEE-CHEUN, RELLING, MARY V · 2015 to 2019
$15.1M
Pathogenesis of ETV6-Related Acute Lymphoblastic LeukemiaR01CA241452 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI NICHOLS, KIM ERIKA · 2020 to 2025
$2.6M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA241452NCI NIH HHS U10 CA098413NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NIGMS NIH HHS P50 GM115279
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Precursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaBasic Helix-Loop-Helix ProteinsChildGerm CellsHumansBasic Helix-Loop-Helix ProteinsTCF3 protein, human

Identifiers

PMID36576946
PMCPMC10196986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.