Evidence map›Paper›PMID 36576664›Full record

ArticleAIDS and behavior2023

Acceptance Rate and Reasons for Rejection of Long Acting Injectable Antiretrovirals.

Dennis Feihel, Daniel Spier, Ty Stevens, Dimitre G Stefanov, Ladan Ahmadi

Abstract read
PubMed Publisher
In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Acceptability, Facilitators, and Barriers of Long-Acting Injectable Cabotegravir/Rilpivirine Among Youth With HIV in the United States.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dennis FeihelNorthwell Health, Zucker School of Medicine at Hofstra/Northwell, Hempstead, 500 Hofstra Blvd, NY, 11549, USA. dfeihel@northwell.edu.ORCID http://orcid.org/0000-0002-9016-3043
Daniel SpierNorthwell Health, Zucker School of Medicine at Hofstra/Northwell, Hempstead, 500 Hofstra Blvd, NY, 11549, USA.
Ty StevensNorthwell Health, Zucker School of Medicine at Hofstra/Northwell, Hempstead, 500 Hofstra Blvd, NY, 11549, USA.
Dimitre G StefanovBiostatistics Unit, Office of Academic Affairs, Northwell Health, New Hyde Park, NY, 11042, USA.
Ladan AhmadiNorthwell Health, Zucker School of Medicine at Hofstra/Northwell, Hempstead, 500 Hofstra Blvd, NY, 11549, USA.
Northwell Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In January 2021, cabotegravir/rilpivirine, the first extended-release injectable regimen for the treatment of Human Immunodeficiency Virus (HIV) was approved. Long-acting injections have the potential to improve adherence and viral suppression. We analyzed the acceptance rate of, and reasons for declining to switch to, the new regimen. During routine appointments, 102 people living with HIV (PLWH) were presented with information on the new medication and asked if they would like to switch from their current regimen. If they declined to switch, they were asked why. Sixty-nine percent of respondents declined to switch, with frequency of injections as the primary reason. Patients indicated they would be willing to switch if the interval between injections was longer. Forty percent of the patients accepting the injectable anti-retrovirals (ARVs) were not on any other medications. Barriers to switching to long-acting injectable ARVs include the need for more frequent provider visits, aversion to needles, and a perceived lack of evidence supporting the new medication.

Indexed as

Anti-HIV AgentsHIV InfectionsAnti-Retroviral AgentsHumansInjectionsRilpivirineAnti-HIV AgentsAnti-Retroviral AgentsRilpivirineAdherenceCabotegravirInjectable

Identifiers

PMID36576664
OpenAlexW4313236742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.