ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2023
Effect of administration of tranexamic acid on blood loss and transfusion requirements in children undergoing posterior fossa tumor excision: a retrospective cohort study.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Pediatric WNT medulloblastoma predisposition in intraoperative blood loss: a retrospective observational cohort study.Frontiers in neurology · 2024Article
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5 authors at 1 institution in 1 country.
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Abstract
backgroundSurgical resection of posterior fossa tumors (PFT) in the pediatric age group often results in significant intraoperative blood loss. The primary objective was to assess the effect of tranexamic acid (TXA) on blood loss and transfusion requirement in pediatric patients undergoing excision of PFT.
methodsIn this retrospective study, all pediatric patients ≤ 18 years, who underwent PFT resection over a period of 7 years, were included. The patient and surgical characteristics, estimated blood loss (EBL), the need for blood and blood product transfusion, use of crystalloids, vasopressors, and any adverse events like seizures and thromboembolic events were recorded and compared between Group A who received TXA and Group B who did not.
resultsThe study included 50 patients, out of which 36 belonged to Group A and 14 to Group B. The median age was 8 years (IQR, 2-17) and the mean BMI was 16.46 ± 4.11 kg/m
conclusionThe use of TXA in the pediatric population undergoing PFT resection aids in reducing blood loss during the surgery without increasing complications.
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