ArticleAnnals of medicine2023
Iron metabolism abnormalities in autoimmune hemolytic anemia and
Article in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 4 citations in OpenAlex.
- Donkey serum albumin improves cyclophosphamide-induced anemia in mice.Open life sciences · 2026Article
- The role of hypothyroidism in cirrhosis pathogenesis: A retrospective cohort study and multi-omics integration analysis.PLoS genetics · 2025Article
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Authors and funding
9 authors at 1 institution in 1 country.
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Abstract
objectiveAutoimmune hemolytic anemia (AIHA) is rare heterogeneous disorder characterized by red blood cell (RBC) destruction via auto-antibodies, and after RBC is destroyed, proinflammatory danger-associated molecular patterns including extracellular hemoglobin, heme, and iron which causing cell injury. And oxidative stress represents one of the most significant effects of chronic hemolysis.
methodsNineteen hemolytic episode AIHA patients, 10 remission patients and 10 healthy controls (HCs) were enrolled in this study. Serum hepcidin, ferritin and other related indicators of iron metabolism were measured. Mouse models of AIHA were established and received high, medium, or low doses of
resultsSerum hepcidin in hemolytic episode AIHA patients and remission patients were significantly higher than that in HCs (
conclusionIron metabolism abnormalities exists in AIHA patients and
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