Evidence map›Paper›PMID 36576255›Full record

ArticleeLife2022

A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite.

Abhinay Ramaprasad, Paul-Christian Burda, Enrica Calvani, Aaron J Sait, Susana Alejandra Palma-Duran, Chrislaine Withers-Martinez, Fiona Hackett, James Macrae, Lucy Collinson, Tim Wolf Gilberger and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Metabolism of host lysophosphatidylcholine inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Cells · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Abhinay Ramaprasad *Malaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0001-9372-5526
Paul-Christian Burda *Centre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0003-0461-4352
Enrica CalvaniMetabolomics Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Aaron J SaitElectron Microscopy Science Technology Platform, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0001-6091-0426
Susana Alejandra Palma-DuranMetabolomics Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Chrislaine Withers-MartinezMalaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom.
Fiona HackettMalaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom.
James MacraeMetabolomics Science Technology Platform, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0002-1464-8583
Lucy CollinsonElectron Microscopy Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Tim Wolf GilbergerCentre for Structural Systems Biology, Hamburg, Germany.ORCID 0000-0002-7965-8272
Michael J BlackmanMalaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0002-7442-3810
The Francis Crick Institute · GBUniversität Hamburg · DE

Funding

Cancer Research UK CC2129Medical Research Council CC2129Wellcome Trust 20318/A/20/ZWellcome Trust CC2129Wellcome Trust ISSF2
6 · The paper itself

Abstract

The malaria parasite

Indexed as

MalariaMalaria, FalciparumParasitesAnimalsCholineErythrocytesGlycerylphosphorylcholinePhosphoric Diester HydrolasesPlasmodium falciparumProtozoan ProteinsCholineglycerophosphodiester phosphodiesteraseGlycerylphosphorylcholinePhosphoric Diester HydrolasesProtozoan Proteinsbiochemistrychemical biologyglycerophosphodiesteraseinfectious diseaselysophosphatidylcholinemalariamicrobiologyP. falciparumphosphatidylcholine synthesisPlasmodium

Identifiers

PMID36576255
PMCPMC9886279
OpenAlexW4313237556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.