Evidence map›Paper›PMID 36575638›Full record

ArticleThe Journal of physiology2023

Lipid phosphate phosphatase 3 maintains NO-mediated flow-mediated dilatation in human adipose resistance arterioles.

Dawid S Chabowski, William E Hughes, Joseph C Hockenberry, John LoGiudice, Andreas M Beyer, David D Gutterman

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Exercise training rescues impaired HAmerican journal of physiology. Heart and circulatory physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dawid S ChabowskiDepartment of Medicine, Division of Cardiology, Medical College of Wisconsin, Milwaukee, WI, USA.
William E HughesDepartment of Medicine, Division of Cardiology, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0002-7580-9213
Joseph C HockenberryDepartment of Medicine, Division of Cardiology, Medical College of Wisconsin, Milwaukee, WI, USA.
John LoGiudiceDepartment of Plastic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Andreas M BeyerDepartment of Medicine, Division of Cardiology, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0001-9129-7492
David D GuttermanDepartment of Medicine, Division of Cardiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Medical College of Wisconsin · US

Funding

Pivotal Role of Mitochondrial Telomerase in Regulation of Vascular Tone and Redox HomeostasisR01HL133029 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI BEYER, ANDREAS M · 2017 to 2021
$2.2M
Critical role of Mitochondrial Fission/Fusion in Regulation of Microvascular Endothelial FunctionR01HL157025 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI BEYER, ANDREAS M · 2021 to 2024
$2.1M
Novel Regulatory Mechanisms in the Human MicrocirculationR01HL135901 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI GUTTERMAN, DAVID D. · 2017 to 2020
$1.7M
Role of Autophagy in Type 2 Diabetes Microvascular DysfunctionR00HL161491 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI William E Hughes · 2024 to 2026
$747k
Role of Autophagy in Type 2 Diabetes Microvascular DysfunctionK99HL161491 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HUGHES, WILLIAM E · 2022 to 2023
$215k
American Heart Association-American Stroke Association 17PRE33410986American Heart Association-American Stroke Association 20POST35050017NHLBI NIH HHS K99 HL161491NHLBI NIH HHS L30 HL154158NHLBI NIH HHS R00 HL161491NHLBI NIH HHS R01 HL133029NHLBI NIH HHS R01-HL133029NHLBI NIH HHS R01 HL135901NHLBI NIH HHS R01-HL-135 901NHLBI NIH HHS R01 HL157025NHLBI NIH HHS R01-HL-157 025
6 · The paper itself

Abstract

Microvascular dysfunction predicts adverse cardiovascular events despite absence of large vessel disease. A shift in the mediator of flow-mediated dilatation (FMD) from nitric oxide (NO) to mitochondrial-derived hydrogen peroxide (H

Indexed as

Coronary Artery DiseaseMicroRNAsAnimalsArteriolesCells, CulturedDilatationHumansNitric OxidePhosphatidate PhosphataseVasodilationlipid phosphate phosphataseMicroRNAsNitric OxidePhosphatidate Phosphatasecoronary artery diseaseflow-mediated dilatationlipid phosphate phosphatase 3miR-92a

Identifiers

PMID36575638
PMCPMC10979460
OpenAlexW4312214480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.