Evidence map›Paper›PMID 36575506›Full record

ArticlePerioperative medicine (London, England)2022

Residual gastric volume after 3 h of the ingestion of an oral supplement containing carbohydrates alone or associated with whey protein: a randomized crossover pilot study.

Paulo Luiz Batista Nogueira, Mario Renato da Silva, Diana Borges Dock-Nascimento, José Eduardo de Aguilar-Nascimento

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Perioperative medicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05573854 (Residual Gastric Volume After the Ingestion of an Oral Supplement Containing Carbohydrates and Whey Protein. A Randomized Crossover Pilot Study), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05573854 nacompletednot on this map

Residual Gastric Volume After the Ingestion of an Oral Supplement Containing Carbohydrates and Whey Protein. A Randomized Crossover Pilot Study

TypeinterventionalSponsorFederal University of Mato GrossoRan2022 to 2022Enrolled6ConditionsFasting, Gastric Stasis, Perioperative Complication, Safety IssuesArmsGastric emptying after an oral supplement containing carbohydrates and whey protein, Overnight Fast
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. PERIOPERATIVE CARE IN DIGESTIVE SURGERY: THE ERAS AND ACERTO PROTOCOLS - BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024
    Guideline
  2. Trial
  3. Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Paulo Luiz Batista NogueiraUNIVAG Medical School, Varzea Grande and Health Sciences Postgraduate Department, Medical School, Federal University of Mato Grosso, Cuiabá, Brazil.
Mario Renato da SilvaDepartment of Radiology, UNIVAG Medical School, Varzea Grande, Brazil.
Diana Borges Dock-NascimentoNutrition School and Health Sciences Postgraduate Department of Medical School, University of Mato Grosso, Cuiabá, Brazil.
José Eduardo de Aguilar-NascimentoUNIVAG Medical School, Varzea Grande and Health Sciences Postgraduate Department, Medical School, Federal University of Mato Grosso, Cuiabá, Brazil. jose.aguilar@univag.edu.br.
Universidade Federal de Mato Grosso · BRCentro Universitário de Várzea Grande · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNew formulas including a nitrogenous source to maltodextrin have been reported as preoperative beverages 2-3 h before anesthesia in the elective procedure. Whey protein is a potential candidate for the composition of this clear oral supplement. This study aimed to investigate the gastric residual volume (GRV) of healthy volunteers 3 h after the ingestion of an oral supplement containing carbohydrates (CHO) alone or combined with whey protein (WP).

methodsThis crossover clinical trial design includes young, healthy male volunteers with normal body mass index. Magnetic resonance imaging (MRI) scan of the upper abdomen to measure the GRV was performed in the participants in three phases: (1) after a fasting period of 8 h; (2) immediately after the ingestion of 200 mL of a clear supplement containing: (2a) 10 g of WP and 54 g of CHO (74% glucose and 26% maltodextrin)-WP + CHO group or (2b) 12.5% maltodextrin (25 g)-CHO group; and (3) after 3 h of the ingestion of both types of supplements. A week interval was programmed between phases 2a and 2b.

resultsThere was no significant difference (p = 0.91; within-group comparison) of the mean ± SD of the GRV between phase 1 (WP + CHO: 23.45 ± 14.01; CHO: 25.03 ± 15.17 cm

conclusionThe GRV after 3 h of the ingestion of either WP + CHO or CHO oral supplement returns to basal fast condition implying that gastric emptying after this interval of time is significantly completed.

trial registrationRegistered and posted on the ClinicalTrials.gov public website with Identifier: NCT05573854.

Indexed as

CarbohydrateGastric emptyingOral supplementPreoperative fastWhey protein

Identifiers

PMID36575506
PMCPMC9793542
OpenAlexW4313250548

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.