Evidence map›Paper›PMID 36575424›Full record

ArticleBMC musculoskeletal disorders2022

Is spinal sagittal alignment of diffuse idiopathic skeletal hyperostosis relevant to thoracolumbar pain? A controlled study.

Shengyu Ruan, Xiaoting Song, Xianquan Xu, Fangying Lu, Chiting Yuan, Binhao Zhang, Tao-Hsin Tung, Dun Hong

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shengyu RuanDepartment of Orthopedics, Taizhou Hospital affiliated to Wenzhou Medical University, Linhai, China.
Xiaoting SongDepartment of Orthopedics, Taizhou Hospital affiliated to Wenzhou Medical University, Linhai, China.
Xianquan XuDepartment of Orthopedics, Taizhou Hospital affiliated to Wenzhou Medical University, Linhai, China.
Fangying LuDepartment of Orthopedics, Taizhou Hospital affiliated to Wenzhou Medical University, Linhai, China.
Chiting YuanDepartment of Orthopedics, Taizhou Hospital affiliated to Wenzhou Medical University, Linhai, China.
Binhao ZhangDepartment of Radiology, Taizhou Hospital affiliated to Wenzhou Medical University, Linhai, China.
Tao-Hsin TungDepartment of Clinical Research, Enze Medical Center, Taizhou, China.
Dun HongDepartment of Orthopedics, Taizhou Hospital affiliated to Wenzhou Medical University, Linhai, China. hongd@enzemed.com.
Wenzhou Medical University · CNZhejiang Taizhou Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe extension of diffuse idiopathic skeletal hyperostosis (DISH) from the low thoracic spine to the lumbar spine result in adjustment of spinal sagittal alignment in surgical patients. The aim of this study was to investigate changes in sagittal alignment and back pain in the thoracolumbar spine in nonsurgical DISH and control participants selected from a radiological database.

methodsParticipants in the DISH and the control group were selected by searching for "DISH or degenerative changes in the thoracic spine" in the radiology database of Taizhou Hospital between 2018 and 2021 using Resnick and Niwayama's criteria. The subjects with spinal tumors, previous spinal surgery, vertebral fractures, inflammatory diseases, poor-quality radiographs, or loss of follow-up were excluded. Demographic and clinical characteristics were recorded retrospectively via the hospital information system and telephone follow-up. Segmental disc angles (SDAs), lumbar lordosis (LL), and bridge scores were analyzed using images of three-dimensional CT.

resultsThe final participants consisted of 51 individuals with DISH (DISH group) and 102 individuals without DISH (control group). Depending on the presence of thoracolumbar pain, the DISH group was divided into the DISH group with thoracolumbar pain (DISH+Pain) and the DISH group without thoracolumbar pain (DISH-Pain). The LL and SDAs of T11-T12 and T12-L1 were significantly greater in the DISH group than in the control group. In addition, the SDA of L1-L2 was significantly smaller in the DISH+Pain group than in the DISH-Pain group, whereas there was no significant difference in lumbar lordosis between the DISH+Pain group and the DISH-Pain group. The bridge scores in DISH+Pain group was larger in T10-T11 (p = 0.01) and L1-L2 (p < 0.01) spine segments than those in DISH-Pain group.

conclusionThe extension of DISH from thoracic to lumbar spine may increase lumbar lordosis and SDAs in the thoracolumbar spine. The DISH patients with more bony bridging and small L1-L2 SDA may be more likely have thoracolumbar pain. Adjustment of sagittal alignment of the spine in the development of DISH may be of clinical importance.

Indexed as

Hyperostosis, Diffuse Idiopathic SkeletalLordosisHumansLumbar VertebraePainRetrospective StudiesThoracic Vertebraeback paindiffuse idiopathic skeletal hyperostosislumbar lordosissegmental disc anglespinal sagittal alignmentsthoracolumbar junction

Identifiers

PMID36575424
PMCPMC9793584
OpenAlexW4312201068

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.