Evidence map›Paper›PMID 36575379›Full record

ArticleGenetics, selection, evolution : GSE2022

A comparison of marker-based estimators of inbreeding and inbreeding depression.

Armando Caballero, Almudena Fernández, Beatriz Villanueva, Miguel A Toro

Open access · goldAbstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
    Article
  4. Faba bean populations already contain the inbreds needed for breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
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  8. Efficiency of Recurrent Genomic Selection in Panmictic Populations.Animals : an open access journal from MDPI · 2025
    Article
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  19. Detecting inbreeding depression in structured populations.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Armando CaballeroCentro de Investigación Mariña, Universidade de Vigo, Facultade de Bioloxía, 36310, Vigo, Spain. armando@uvigo.es.ORCID http://orcid.org/0000-0001-7391-6974
Almudena FernándezDepartamento de Mejora Genética Animal, INIA-CSIC, Ctra. de La Coruña, Km 7.5, 28040, Madrid, Spain.
Beatriz VillanuevaDepartamento de Mejora Genética Animal, INIA-CSIC, Ctra. de La Coruña, Km 7.5, 28040, Madrid, Spain.
Miguel A ToroDepartamento de Producción Agraria, ETSI Agronómica, Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, 28040, Madrid, Spain.
Consejo Superior de Investigaciones Científicas · ESUniversidade de Vigo · ESUniversidad Politécnica de Madrid · ES

Funding

European Maritime and Fisheries Fund PRTR-C17.I1Ministerio de Ciencia e Innovación PID2020-114426GBSecretaria Xeral de Investigación e Desenvolvemento, Xunta de Galicia ED431C 2020-05
6 · The paper itself

Abstract

backgroundThe availability of genome-wide marker data allows estimation of inbreeding coefficients (F, the probability of identity-by-descent, IBD) and, in turn, estimation of the rate of inbreeding depression (ΔID). We investigated, by computer simulations, the accuracy of the most popular estimators of inbreeding based on molecular markers when computing F and ΔID in populations under random mating, equalization of parental contributions, and artificially selected populations. We assessed estimators described by Li and Horvitz (F

resultsIf the allele frequencies of a base population taken as a reference for the computation of inbreeding are known, all estimators based on marker allele frequencies are highly correlated with F

conclusionsWhen base population allele frequencies are known, all marker-allele frequency-based estimators of inbreeding coefficients generally show a high correlation with F

Indexed as

Inbreeding DepressionInflammatory Bowel DiseasesAnimalsGenotypeHomozygoteInbreedingPedigreePolymorphism, Single NucleotideSwine

Identifiers

PMID36575379
PMCPMC9793638
OpenAlexW4313249054

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.