ArticleNature communications2022
High-frequency synthetic apomixis in hybrid rice.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 103 citations in OpenAlex.
- Development of a low-coverage whole genome sequencing screen for apomixis using a diverse set of Malus germplasm.PLoS genetics · 2026Article
- Innovations in hybrid rice seed production: Integrating agronomy, mechanization, and biotechnology.Plant communications · 2026Review
- Successful transfer of apomixis leads to heritable semi-sterility in experimental apomictic hybrids of Hieracium s.str. (Asteraceae).Plant biology (Stuttgart, Germany) · 2026Article
- TIE1 acts as a maternal brake on fertilization-independent endosperm development by associating with PRC2 to enforce imprinting.Nature plants · 2026Article
- Genome-Wide Identification of AP2/ERF Transcription Factors inPlants (Basel, Switzerland) · 2026Article
- Identification of different cDNA clones of the Apomixis-specific gene-1 homolog involved in aposporous embryo sac formation in guineagrass (Plant biotechnology (Tokyo, Japan) · 2026Article
- Article
- Engineering high-fertility synthetic apomixis in hybrid rice via genome editing of MiMe and OspPLAIIκ.Science China. Life sciences · 2026Article
- Paradigm shift in apomixis research: Targeting mutants with elements of apomixis in sexual crops.Planta · 2026Review
- Basis of apomixis in flowering plants - state of the art and research perspectives.Plant reproduction · 2026Review
- Stepwise construction of the path to doubled haploid breeding in sorghum.Science advances · 2026Article
- A Precise Reproductive Calendar of Sexual and Apomictic Genotypes ofPlants (Basel, Switzerland) · 2026Article
- Induction of Synthetic Apomixis in Two Sorghum Hybrids Enables Seed Yield and Genotype Preservation Over Multiple Generations.Plant biotechnology journal · 2026Article
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- High-frequency synthetic apomixis byFrontiers in plant science · 2026Article
- Gametophytic Apomixis: An Introduction.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Engineering Synthetic Apomixis in Hybrid Rice.Methods in molecular biology (Clifton, N.J.) · 2026Article
- The Potential of NGTs to Overcome Constraints in Plant Breeding and Their Regulatory Implications.International journal of molecular sciences · 2025Review
- Harnessing apomixis: natural mechanisms and synthetic innovations for advancing crop and forage breeding.Horticulture research · 2025Article
- Extending Mendel's legacy: Application of hawkweed PpPAR for inducing synthetic apomixis in hybrid rice.Plant communications · 2025Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introducing asexual reproduction through seeds - apomixis - into crop species could revolutionize agriculture by allowing F1 hybrids with enhanced yield and stability to be clonally propagated. Engineering synthetic apomixis has proven feasible in inbred rice through the inactivation of three genes (MiMe), which results in the conversion of meiosis into mitosis in a line ectopically expressing the BABYBOOM1 (BBM1) parthenogenetic trigger in egg cells. However, only 10-30% of the seeds are clonal. Here, we show that synthetic apomixis can be achieved in an F1 hybrid of rice by inducing MiMe mutations and egg cell expression of BBM1 in a single step. We generate hybrid plants that produce more than 95% of clonal seeds across multiple generations. Clonal apomictic plants maintain the phenotype of the F1 hybrid along successive generations. Our results demonstrate that there is no barrier to almost fully penetrant synthetic apomixis in an important crop species, rendering it compatible with use in agriculture.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.