ArticleProceedings of the National Academy of Sciences of the United States of America2023
Iontronic analog of synaptic plasticity: Hydrogel-based ionic diode with chemical precipitation and dissolution.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 55 citations in OpenAlex.
- Instability-driven electrohydrodynamic neurons for probabilistic computing.Nature communications · 2026Article
- Fully Printed Ionic Diodes from Polymerizable Ionic Liquids.ACS nano · 2026Article
- Soft Iontronic Diodes: Materials, Mechanisms, and Progress.Gels (Basel, Switzerland) · 2026Review
- Self-heating-induced blocking in nanopores enables neuromorphic ionic computing.Nature communications · 2026Article
- Bioinspired Nanofluidic Memristors Based on Polyelectrolyte Conformation for Synaptic Learning and in-Memory Logic Computing.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Gel-Based Ionic Circuits.Chemical reviews · 2025Review
- Neuromorphic Reservoir Computing with Memristive Nanofluidic Diodes.Nano letters · 2025Article
- Aqueous power source integrated on a microfluidic chip.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Bioactive Ion-Confined Ultracapacitive Memristors with Neuromorphic Functions.Angewandte Chemie (International ed. in English) · 2024Article
- Bioinspired iontronic synapse fibers for ultralow-power multiplexing neuromorphic sensorimotor textiles.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Highly stretchable dynamic hydrogels for soft multilayer electronics.Science advances · 2024Article
- Geometrically Scalable Iontronic Memristors: Employing Bipolar Polyelectrolyte Gels for Neuromorphic Systems.ACS nano · 2024Article
- Mimicking Bidirectional Inhibitory Synapse Using a Porous-Confined Ionic Memristor with Electrolyte/Tris(4-aminophenyl)amine Neurotransmitter.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Brain-inspired computing with fluidic iontronic nanochannels.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Streamlining the interface between electronics and neural systems for bidirectional electrochemical communication.Chemical science · 2023Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, an aqueous nonlinear synaptic element showing plasticity behavior is developed, which is based on the chemical processes in an ionic diode. The device is simple, fully ionic, and easily configurable, requiring only two terminals-for input and output-similar to biological synapses. The key processes realizing the plasticity features are chemical precipitation and dissolution, which occur at forward- or reverse-biased ionic diode junctions in appropriate reservoir electrolytes. Given that the precipitate acts as a physical barrier in the circuit, the above processes change the diode conductivity, which can be interpreted as adjusting "synaptic weight" of the system. By varying the operating conditions, we first demonstrate the four types of plasticity that can be found in biological system: long-term potentiation/depression and short-term potentiation/depression. The plasticity of the proposed iontronic device has characteristics similar to those of neural synapses. To demonstrate its potential use in comparatively complex information processing, we develop a precipitation-based iontronic synapse (PIS) capable of both potentiation and depression. Finally, we show that the postsynaptic signals from the multiple excitatory or inhibitory PISs can be integrated into the total "dendritic" current, which is a function of time and input history, as in actual hippocampal neural circuits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.