ArticleAJNR. American journal of neuroradiology2022
Diagnostic Accuracy of MRI for Detection of Meningitis in Infants.
Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Recent advancements in pediatric purulent meningitis: diagnosis and treatment.Italian journal of pediatrics · 2026Review
- Persistent meningeal enhancement on MRI in an infant with culture-negative bacterial meningitis: a case report and systematic review of the literature (2014-2025).Frontiers in pediatrics · 2026Article
- Amelanotic melanoma of the central nervous system with systemic spread - imaging pitfalls and clues in a rare paediatric case with congenital melanocytic naevi.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- A novel MRI-based deep learning-radiomics framework for evaluating cerebrospinal fluid signal in central nervous system infection.Frontiers in medicine · 2025Article
- Pediatric Meningeal Diseases: What Radiologists Need to Know.Tomography (Ann Arbor, Mich.) · 2024Review
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the accuracy of MR imaging for diagnosis of meningitis in infants. MATERIALS AND
methodsRetrospective review of infants less than 1 year of age who underwent a brain MR imaging for meningitis from 2010-2018. Gold standard for diagnosis of bacterial meningitis was a positive bacterial CSF culture or a positive blood culture with an elevated CSF WBC count, and diagnosis of viral meningitis was a positive CSF PCR result and elevated CSF WBC count. Sensitivity, specificity, PPV, NPV, and accuracy for MR imaging diagnosis of meningitis were calculated.
resultsTwo hundred nine infants with mean age 80 days (range 0-347 days) were included. There were 178 true positives with the most common pathogens being:
conclusionsMR imaging of the brain demonstrates high specificity and moderate sensitivity for diagnosis among infants presenting with signs and symptoms of meningitis. The results reflect current standard of care for imaging of infants with meningitis however a selection bias for imaging of more severe meningitis may affect these results.
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