ReviewUnfallchirurgie (Heidelberg, Germany)2023
[Biological reconstruction of large bone defects : Masquelet technique and new procedures].
Review in Unfallchirurgie (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 6 citations in OpenAlex.
- PMMA-induced membranous angiogenesis accelerates wound healing in refractory diabetic foot ulcers: A comparative cohort study.JPRAS open · 2026Article
- 3D printed microporous titanium prosthesis for single implantation or combined with free flap for infected bone defects in the limbs: a single-center retrospective cohort study.BMC musculoskeletal disorders · 2026Article
- Clinical efficacy of Masquelet technique in the treatment of tibial and fibular bone defects caused by severe gunshot wounds.Frontiers in medicine · 2026Article
- [Treatment of bony defects in femur and tibia : Established and new concepts].Unfallchirurgie (Heidelberg, Germany) · 2025Article
- Multistage surgical strategy combining bone transport and antibiotic cement in a complex lower extremity crush injury: achieving limb salvage and infection control.BMC musculoskeletal disorders · 2025Article
- Therapeutic effect of modified iliac bone graft combined with antibiotic bone cement on lower limb bone infection complicated with large segment bone defect: An Observational Study.African health sciences · 2025Observational
- The Concept of Scaffold-Guided Bone Regeneration for the Treatment of Long Bone Defects: Current Clinical Application and Future Perspective.Journal of functional biomaterials · 2023Review
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extensive diaphyseal and metaphyseal bone defects continue to pose a major challenge for orthopedic trauma surgeons. Various treatment options have been described for the biological reconstruction of these defects. The most frequently used methods are bone segment transport, the Masquelet technique and 3D printed scaffolds. As far as the Masquelet technique is concerned, in the first stage spacers, such as polymethyl methacrylate (PMMA), calcium sulfate or polypropylene are inserted into the bone defects to induce a foreign body membrane. In the second stage the bone defect surrounded by the induced membrane is filled with autologous cancellous bone. The time interval between the first and second interventions is usually 4-8 weeks whereby the induced membranes do not lose their bioactivity even with a latency period longer than 8 weeks. Three-dimensional printed scaffolds are increasingly used but large clinical studies are lacking in order to show the exact role of this procedure in the reconstruction of bone defects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.