Evidence map›Paper›PMID 36573593›Full record

ArticleEmerging infectious diseases2023

Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan.

Irene Molina-de la Fuente, María José Sagrado Benito, Laurence Flevaud, Janet Ousley, Harriet Akello Pasquale, Ahmed Julla, Abdirashid M Abdi, Buai Tut Chol, Bakri Abubakr, Agustín Benito and 3 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Local variability inMalariaWorld journal · 2026
    Article
  4. A NovelmedRxiv : the preprint server for health sciences · 2025
    Article
  5. Article
  6. Malaria diagnosis challenges andPathogens and global health · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Irene Molina-de la Fuente
María José Sagrado Benito
Laurence Flevaud
Janet Ousley
Harriet Akello Pasquale
Ahmed Julla
Abdirashid M Abdi
Buai Tut Chol
Bakri Abubakr
Agustín Benito
Cristian Casademont
Carolina Nanclares
Pedro Berzosa

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for pfhrp3, and 7.5% for double deletions. Deletions were approximately twice as prevalent in monoclonal infections than in polyclonal infections.

Indexed as

Malaria, FalciparumPlasmodium falciparumAntigens, ProtozoanDiagnostic Tests, RoutineGene DeletionHumansProtozoan ProteinsSouth SudanAntigens, ProtozoanProtozoan Proteinsdiagnosishistidine-rich proteinmalariamolecular epidemiologyparasitesPlasmodium falciparumRDTSouth Sudansurveillancevector-borne infections

Identifiers

PMID36573593
PMCPMC9796199

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.