Evidence map›Paper›PMID 36573545›Full record

ArticleEmerging infectious diseases2023

High SARS-CoV-2 Seroprevalence after Second COVID-19 Wave (October 2020-April 2021), Democratic Republic of the Congo.

Yannick Munyeku-Bazitama, Gervais T Folefack, Marc K Yambayamba, Paul M Tshiminyi, Benito M Kazenza, John O Otshudiema, Noe Tondri Guinko, Moreau D Umba, Anastasie Mulumba, Lionel K Baketana and 5 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yannick Munyeku-Bazitama
Gervais T Folefack
Marc K Yambayamba
Paul M Tshiminyi
Benito M Kazenza
John O Otshudiema
Noe Tondri Guinko
Moreau D Umba
Anastasie Mulumba
Lionel K Baketana
Patrick K Mukadi
Chris Smith
Jean-Jacques Muyembe-Tamfum
Steve Ahuka-Mundeke
Sheila Makiala-Mandanda

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serologic surveys are important tools for estimating the true burden of COVID-19 in a given population. After the first wave of SARS-CoV-2 infections, a household-based survey conducted in Kinshasa, Democratic Republic of the Congo, estimated >292 infections going undiagnosed for every laboratory-confirmed case. To ascertain the cumulative population exposure in Kinshasa after the second wave of COVID-19, we conducted a prospective population-based cross-sectional study using a highly sensitive and specific ELISA kit. The survey included 2,560 consenting persons from 585 households; 55% were female and 45% male. The overall population-weighted, test kit-adjusted SARS-CoV-2 seroprevalence was 76.5% (95% CI 74.5%-78.5%). The seroprevalence was 4-fold higher than during the first wave, and positivity was associated with age, household average monthly income, and level of education. Evidence generated from this population-based survey can inform COVID-19 response, especially vaccination campaign strategies in the context of vaccine shortages and hesitancy.

Indexed as

COVID-19Antibodies, ViralCross-Sectional StudiesDemocratic Republic of the CongoFemaleHumansMaleProspective StudiesSARS-CoV-2Seroepidemiologic StudiesAntibodies, Viralcoronavirus diseaseCOVID-19Democratic Republic of the CongoKinshasarespiratory infectionsSARS-CoV-2second waveseroprevalencesevere acute respiratory syndrome coronavirus 2vaccine-preventable diseasesviruseszoonoses

Identifiers

PMID36573545
PMCPMC9796206

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.