ArticleThe British journal of nutrition2023
Fat and lean mass predict time to hospital readmission or mortality in children treated for complicated severe acute malnutrition in Zimbabwe and Zambia.
Article in The British journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Restoration of anti-bacterial innate immune cell function lags behind nutritional recovery among children convalescing from complicated severe acute malnutrition.Nature communications · 2026Article
- Anthropometric and Body-Composition Changes in Severely Acute Malnourished Children (12-59 Months) Post-Nutritional Rehabilitation: A Follow-Up Study.Pediatric gastroenterology, hepatology & nutrition · 2025Article
- Adaptive Responses in Severe Acute Malnutrition: Endocrinology, Metabolomics, Mortality, and Growth.Nutrients · 2025Review
- Mitochondrial perturbations in low-protein-diet-fed mice are associated with altered neutrophil development and effector functions.Cell reports · 2024Article
- Pediatric post-discharge mortality in resource-poor countries: a systematic review and meta-analysis.EClinicalMedicine · 2024Article
- Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells.Science advances · 2023Article
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 4 countries.
Funding
Abstract
HIV and severe wasting are associated with post-discharge mortality and hospital readmission among children with complicated severe acute malnutrition (SAM); however, the reasons remain unclear. We assessed body composition at hospital discharge, stratified by HIV and oedema status, in a cohort of children with complicated SAM in three hospitals in Zambia and Zimbabwe. We measured skinfold thicknesses and bioelectrical impedance analysis (BIA) to investigate whether fat and lean mass were independent predictors of time to death or readmission. Cox proportional hazards models were used to estimate the association between death/readmission and discharge body composition. Mixed effects models were fitted to compare longitudinal changes in body composition over 1 year. At discharge, 284 and 546 children had complete BIA and skinfold measurements, respectively. Low discharge lean and peripheral fat mass were independently associated with death/hospital readmission. Each unit
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Registered trials
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