Evidence map›Paper›PMID 36573240›Full record

ArticlePeerJ2022

Ying Wang, Yadong Li, Xuanwei Jiang, Yayun Gu, Hui Zheng, Xiaoxuan Wang, Haotian Zhang, Jixiang Wu, Yang Cheng

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. The Role of N6-Methyladenosine in Mitochondrial Dysfunction and Pathology.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. [Research progress of optic atrophy 1-mediated mitochondrial dynamics in skeletal system diseases].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ying Wang *Center for Health Management, Jiangsu Province Geriatric Hospital, Nanjing, China.
Yadong Li *Department of Thoracic Surgery, The Second Clinical Medical College of Nanjing Medical University, Nanjing, China.
Xuanwei JiangState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Yayun GuState Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Hui ZhengCenter for Health Management, Jiangsu Province Geriatric Hospital, Nanjing, China.
Xiaoxuan WangState Key Laboratory of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd., Nanjing, China.
Haotian ZhangThe First Clinical Medical College of Nanjing Medical University, Nanjing, China.
Jixiang WuDepartment of Thoracic and Cardiovascular Surgery, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng, China.
Yang ChengCenter for Health Management, Jiangsu Province Geriatric Hospital, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CNSecond Affiliated Hospital of Nanjing Medical University · CNSimcere Pharmaceutical (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mitochondrial fusion and fission were identified to play key roles during multiple biology process. Thus, we aim to investigate the roles of OPA1 in mitochondria fusion and immune evasion of non-small cell lung cancer cells. Methods: The transcriptional activation of genes related to mitochondrial dynamics was determined by using multi-omics data in lung adenocarcinoma (LUAD). We elucidated the molecular mechanism and roles of OPA1 promoting lung cancer through single-cell sequencing and molecular biological experiments. Results: Here, we found that copy number amplification of Conclusions: Our study demonstrated the high co-occurrence of copy number amplification and co-expression of

Indexed as

Adenocarcinoma of LungCarcinoma, Non-Small-Cell LungLung NeoplasmsCD8-Positive T-LymphocytesGTP PhosphohydrolasesHumansImmune EvasionMitochondrial DynamicsGTP PhosphohydrolasesOPA1 protein, humanCD8+ T cellImmune evasionLung adenocarcinomaMitochondrial fusionOPA1

Identifiers

PMID36573240
PMCPMC9789695
OpenAlexW4313278758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.