Evidence map›Paper›PMID 36573097›Full record

ReviewACS bio & med chem Au2022

Activity-Based Sensing for Chemistry-Enabled Biology: Illuminating Principles, Probes, and Prospects for Boronate Reagents for Studying Hydrogen Peroxide.

Marco S Messina, Gianluca Quargnali, Christopher J Chang

Abstract readReview
In one paragraph

Review in ACS bio & med chem Au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marco S MessinaDepartment of Chemistry and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, United States.ORCID https://orcid.org/0000-0003-2827-118X
Gianluca QuargnaliDepartment of Chemistry and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, United States.ORCID https://orcid.org/0000-0001-5626-4273
Christopher J ChangDepartment of Chemistry and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, United States.ORCID https://orcid.org/0000-0001-5732-9497

Funding

Molecular Imaging Probes To Study Redox BiologyR01GM079465 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2006 to 2026
$7.8M
Chemical Probes to Study Formaldehyde BiologyR01ES028096 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2017 to 2026
$4.1M
Chemical Probes to Study Methionine Redox BiologyR01GM139245 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2020 to 2026
$2.9M
An Activity-Based Biomolecule Labeling Platform for the Imaging of Cells and Tissues Under Oxidative StressK99GM143573 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MESSINA, MARCO · 2021 to 2022
$160k
NIEHS NIH HHS R01 ES028096NIGMS NIH HHS K99 GM143573NIGMS NIH HHS R01 GM079465NIGMS NIH HHS R01 GM139245
6 · The paper itself

Abstract

Activity-based sensing (ABS) offers a general approach that exploits chemical reactivity as a method for selective detection and manipulation of biological analytes. Here, we illustrate the value of this chemical platform to enable new biological discovery through a case study in the design and application of ABS reagents for studying hydrogen peroxide (H

Identifiers

PMID36573097
PMCPMC9782337

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.