Evidence map›Paper›PMID 36573033›Full record

ArticleJournal of intellectual disability research : JIDR2023

Confirmatory factor analysis of the BRIEF2 in a sample of youth with Down syndrome.

A Soltani, E K Schworer, L A Jacobson, M M Channell, N R Lee, G G Faught, R Grzadzinski, D Fidler, A J Esbensen

Abstract read
In one paragraph

Article in Journal of intellectual disability research : JIDR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Longitudinally Predicting Behavioral Challenges From Executive Functioning in Youth With Down Syndrome.American journal on intellectual and developmental disabilities · 2025
    Article
  3. Article
  4. Confirmatory factor analysis of the BRIEF2 in a sample of youth with Down syndrome.Journal of intellectual disability research : JIDR · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A SoltaniDepartment of Educational Psychology, Kerman Branch, Islamic Azad University, Kerman, Iran.
E K SchworerDivision of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID 0000-0002-5309-339X
L A JacobsonDepartment of Neuropsychology, Kennedy Krieger Institute; Department of Psychiatry and Behavioral Sciences, John Hopkins University, Baltimore, MD, USA.
M M ChannellDepartment of Speech and Hearing Science, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
N R LeeDepartment of Psychological and Brain Sciences, Drexel University, Philadelphia, PA, USA.
G G FaughtDepartment of Psychology, The University of Alabama, Tuscaloosa, AL, USA.ORCID 0000-0001-5644-7424
R GrzadzinskiCarolina Institute for Developmental Disabilities, University of North Carolina, Carrboro, NC, USA.
D FidlerDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0001-6208-456X
A J EsbensenDivision of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID 0000-0003-2649-7791

Funding

Cellular and molecular mechanisms governing cortical surface area overgrowth in iPSC-derived neural cells from longitudinally characterized individuals with autismR01HD055741 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph Piven · 2007 to 2026
$52.6M
North Carolina Translational and Clinical Science Institute (NC TraCS) KL2KL2TR002490 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEINBERGER, MORRIS · 2018 to 2022
$11.0M
Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JUDY A. VAN DE WATER · 2020 to 2026
$9.7M
Translational Neuroscience CoreU54HD079123 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI FATEMI, S. ALI, SCHLAGGAR, BRADLEY L · 2014 to 2019
$7.9M
INCLUDE19 – Evaluating outcome measures in young adults with Down syndromeR01HD093754 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI Anna J. Esbensen · 2018 to 2026
$6.2M
POSTDOCTORAL TRAINING IN MENTAL RETARDATION RESEARCHT32HD007489 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Sigan L Hartley · 1995 to 2026
$6.0M
Executive Function Outcome Measures for Young Children with Down SyndromeR01HD099150 · NICHD · COLORADO STATE UNIVERSITY · PI DEBORAH J FIDLER · 2019 to 2026
$4.7M
Evaluating Assessment and Medication Treatment of ADHD in Children with Down SyndromeR33HD100934 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI ESBENSEN, ANNA J., FROEHLICH, TANYA E. · 2022 to 2024
$4.2M
Memory Measures for Clinical Trials in Down syndrome and Fragile X syndromeR01HD088409 · NICHD · UNIVERSITY OF ARIZONA · PI EDGIN, JAMIE O. · 2016 to 2020
$3.7M
Evaluating Assessment and Medication Treatment of ADHD in Children with Down SyndromeR61HD100934 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI ESBENSEN, ANNA J., FROEHLICH, TANYA E. · 2019 to 2021
$1.5M
Executive dysfunction as a treatment target for DS clinical trials: An evaluation of its real-world and neural correlates.R21HD106164 · NICHD · DREXEL UNIVERSITY · PI LEE, NANCY RAITANO, WALLACE, GREGORY L · 2021 to 2022
$541k
NCATS NIH HHS KL2 TR002490NCATS NIH HHS KL2TR002490NICHD NIH HHS P50 HD103526NICHD NIH HHS P50 HD103538NICHD NIH HHS R01 HD055741NICHD NIH HHS R01 HD088409NICHD NIH HHS R01 HD093754NICHD NIH HHS R01 HD099150NICHD NIH HHS R03 HD083596NICHD NIH HHS R21 HD100997NICHD NIH HHS R21 HD101000NICHD NIH HHS R21 HD106164NICHD NIH HHS R33 HD100934NICHD NIH HHS R61 HD100934NICHD NIH HHS T32 HD007489NICHD NIH HHS U54 HD079123
6 · The paper itself

Abstract

backgroundThe factor structure of the Behavior Rating Inventory of Executive Function, second edition (BRIEF2) has been widely examined in both typically developing children and specific clinical samples. Despite the frequent use of the BRIEF2 for measuring executive functioning in individuals with Down syndrome, no study has investigated the factorial validity or dimensionality of the BRIEF2 in this population. This study aimed to address this notable gap in the literature.

methodsParents of 407 children and youth with Down syndrome aged 6-18 years completed the BRIEF2 as part of different studies led by six sites. Three competing models proposed by previous studies were analysed using Confirmatory Factor Analysis: the theoretical structure of the BRIEF2 where the scales were constrained to load on three factors labelled as Cognitive, Behavioral, and Emotional Regulation, a two-factor correlated model with the merged Behavioral and Emotional regulation, and a single-factor model.

resultsThe three-factor model provided a better fit than the one- and two-factor models, yet a large correlation was observed between Behavioural and Emotional regulation factors. The results provide meaningful explanatory value for the theoretical structure of the BRIEF2. However, the Behavioral and Emotional regulation factors might be less differentiated and the two-factor structure of the BRIEF2 may also make theoretical and empirical sense.

conclusionsAlthough more studies are needed to further examine the factor structure of the BRIEF2 in youth with Down syndrome, this investigation provides preliminary support for the interpretation of the three executive function index scores provided by the BRIEF2: Cognitive, Behavioral, and Emotional Regulation.

Indexed as

Down SyndromeAdolescentChildExecutive FunctionFactor Analysis, StatisticalHumansParentsPsychometricsBRIEF2CFADown syndromeExecutive functioningTrisomy 21

Identifiers

PMID36573033
PMCPMC9839560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.