Evidence map›Paper›PMID 36572846›Full record

ArticleBMC pediatrics2022

Rates of confirmatory HIV testing, linkage to HIV services, and rapid initiation of antiretroviral treatment among newly diagnosed children living with HIV in Ethiopia: perspectives from caregivers and healthcare workers.

Alemayehu Bekele, Susan Hrapcak, Jelaludin Ahmed Mohammed, Jemal Ayalew Yimam, Tsegaye Tilahun, Tenagnework Antefe, Hanna Kumssa, Desta Kassa, Semegnew Mengistu, Kelsey Mirkovic and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Alemayehu Bekele *Ethiopian Public Health Association, Addis Ababa, Ethiopia. alemayehubekele2002@yahoo.com.
Susan Hrapcak *Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jelaludin Ahmed MohammedCenters for Disease Control and Prevention, Addis Ababa, Ethiopia.
Jemal Ayalew YimamEthiopian Public Health Association, Addis Ababa, Ethiopia.
Tsegaye TilahunUnited States Agency for International Development, Addis Ababa, Ethiopia.
Tenagnework AntefeAmhara Regional Health Bureau, Amhara, Ethiopia.
Hanna KumssaAddis Ababa City Administration Health Bureau, Addis Ababa, Ethiopia.
Desta KassaEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Semegnew MengistuEthiopian Public Health Association, Addis Ababa, Ethiopia.
Kelsey MirkovicCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Eric J DziubanCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Zena BelayCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Christine RossCenters for Disease Control and Prevention, Addis Ababa, Ethiopia.
Wondimu TeferiCenters for Disease Control and Prevention, Addis Ababa, Ethiopia.
Centers for Disease Control and Prevention · USAfrica Centres for Disease Control and Prevention · ETEthiopian Public Health Association · ETAddis Ababa City Administration Health Bureau · ETAmhara Regional Health Bureau · ETEthiopian Public Health Institute · ETUnited States Agency for International Development · US

Funding

PEPFAR
6 · The paper itself

Abstract

backgroundSuccessful linkage to HIV services and initiation of antiretroviral treatment (ART) for children living with HIV (CLHIV) is critical to improve pediatric ART coverage. We aimed to assess confirmatory testing, linkage, and rapid ART initiation among newly diagnosed CLHIV in Ethiopia from the perspectives of caregivers and healthcare workers (HCWs).

methodsWe conducted standardized surveys with HCWs and caregivers of children 2-14 years who were diagnosed with HIV but not yet on ART who had been identified during a cross-sectional study in Ethiopia from May 2017-March 2018. Eight health facilities based on their HIV caseload and testing volume and 21 extension sites were included. Forty-one children, 34 care givers and 40 healthcare workers were included in this study. Three months after study enrollment, caregivers were surveyed about timing and experiences with HIV service enrollment, confirmatory testing, and ART initiation. Data collected from HCWs included perceptions of confirmatory testing in CLHIV before ART initiation. SPSS was used to conduct descriptive statistics.

resultsThe majority of the 41 CLHIV were enrolled to HIV services (n = 34, 83%) and initiated ART by three months (n = 32, 94%). Median time from diagnosis to ART initiation was 12 days (interquartile range 5-18). Five children died before the follow-up interview. Confirmatory HIV testing was conducted in 34 children and found no discordant results; the majority (n = 23, 68%) received it within one week of HIV diagnosis. Almost all HCWs (n = 39/40, 98%) and caregivers (n = 31/34, 91%) felt better/the same about test results after conducting confirmatory testing.

conclusionOpportunities remain to strengthen linkage for newly diagnosed CLHIV in Ethiopia through intensifying early follow-up to ensure prompt confirmatory testing and rapid ART initiation. Additional services could help caregivers with decision-making around treatment initiation for their children.

Indexed as

Anti-HIV AgentsHIV InfectionsAnti-Retroviral AgentsCaregiversChildCross-Sectional StudiesEthiopiaHealth PersonnelHIV TestingHumansAnti-HIV AgentsAnti-Retroviral AgentsChildrenConfirmatory testingEnrollmentHIVLinkageRapid ART initiation

Identifiers

PMID36572846
PMCPMC9791729
OpenAlexW4312218473

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.