ArticleCell death & disease2022
Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia/reperfusion injury via suppressing GPX4-mediated ferroptosis.
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Article in Cell death & disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
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Who cites it
44 citing papers in PubMed, 65 citations in OpenAlex.
- STAT1: a central hub linking ferroptosis and inflammation in hepatic ischemia-reperfusion injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Review
- P53 Competitively Binds P300 to Suppress HIF-1α/TFRC-Mediated Ferroptosis and Promote Doxorubicin Resistance in Breast Cancer.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury.World journal of transplantation · 2026Review
- FSP1 reduces exogenous coenzyme Q10 and inhibits ferroptosis to alleviate intestinal ischemia-reperfusion injury.Journal of advanced research · 2026Article
- An integrated approach combining computational analyses and experimental validation deciphers the mechanism and active substance basis of Huazhuo Ningfu decoction in treating psoriasis.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Immune Determinants of MASLD Progression: From Immunometabolic Reprogramming to Fibrotic Transformation.Biology · 2026Review
- Sterile Inflammation and Cell Death Pathways in Liver Ischemia-Reperfusion Injury: A Review and Perspective.Endocrine, metabolic & immune disorders drug targets · 2026Review
- Hypoxia-preconditioning human bone marrow-derived mesenchymal stem cells induce high-quality mitochondrial transfer through gap junctions to alleviate ischemia-reperfusion injury in liver graft.Cell communication and signaling : CCS · 2025Article
- STAT1 promotes ferroptosis and inflammation in mouse hepatic ischemia-reperfusion injury.Communications biology · 2025Article
- Ferroptosis: biology and role in liver disease.Journal of gastroenterology · 2025Review
- Transmembrane protein TMEM98 as a multifunctional regulator in cancer: from signaling pathways to translational implications.Journal of translational medicine · 2025Review
- Nuclear receptor FXR inhibits ferroptosis to alleviate hepatic ischemia-reperfusion injury by targeting GPX4 in a mouse model.Journal of molecular histology · 2025Article
- FXR acts as a therapeutic target for ulcerative colitis via suppressing ferroptosis.Molecular medicine (Cambridge, Mass.) · 2025Article
- USP5-induced deubiquitination of P4HB alleviates ER stress-mediated apoptosis in intestinal ischemia/reperfusion.Cellular and molecular life sciences : CMLS · 2025Article
- The function of chloride channels in digestive system disease (Review).International journal of molecular medicine · 2025Review
- Ceramide(d18:1/18:1)-NDUFA6 interaction inactivates respiratory complex I to attenuate oxidative-stress-driven pathogenesis in liver ischemia/reperfusion injury.JCI insight · 2025Article
- TXNIP knockdown ameliorates hepatic ischemia/reperfusion injury by inhibiting apoptosis and improving mitochondrial dysfunction via HIF-1α.Molecular and cellular biochemistry · 2025Article
- Insulin-induced gene 2 alleviates ischemia-reperfusion injury in steatotic liver by inhibiting GPX4-dependent ferroptosis.Cell death discovery · 2025Article
- Mesenchymal Stem Cells Prevent SLC39A14-Dependent Hepatocyte Ferroptosis through Exosomal miR-16-5p in Liver Graft.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Ferroptosis in organ ischemia-reperfusion injuries: recent advancements and strategies.Molecular and cellular biochemistry · 2025Review
Corrections and comments
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Authors and funding
18 authors at 9 institutions in 2 countries.
Jiawei Guo *Department of Pharmacology, School of Medicine, Yangtze University, Jingzhou, China. guojw9@mail2.sysu.edu.cn.ORCID 0000-0001-9471-2508
Zihao Song *Department of Immunology, School of Medicine, Yangtze University, Jingzhou, China.
Jie Yu *Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Chengyi LiDepartment of Immunology, School of Medicine, Yangtze University, Jingzhou, China.
Chenchen JinCenter for Neuro-Metabolism and Regeneration Research, The Bioland Laboratory, Guangzhou, China.
Wei DuanDepartment of Oncology, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
Xiu LiuDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yingying LiuGuangzhou Women and Children's Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Shuai HuangDepartment of Orthopaedic Surgery, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yonghua TuoDepartment of Neurosurgery, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Fei PeiDepartment of Critical Care Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhengyang JianCenter For Drug Inspection of Guizhou Medical Products Administration, Guiyang, China.
Pengyu ZhouDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Shaoyi ZhengDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhaowei ZouDepartment of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Feng ZhangDepartment of Radiology, University of Washington School of Medicine, Seattle, WA, USA.
Quan GongDepartment of Immunology, School of Medicine, Yangtze University, Jingzhou, China. gongquan@yangtzeu.edu.cn.
Sijia LiangDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China. liangsj5@mail.sysu.edu.cn.ORCID 0000-0002-4014-6325
Yangtze University · CNNanfang Hospital · CNSecond Affiliated Hospital of Guangzhou Medical University · CNSun Yat-sen University · CNZhujiang Hospital · CNGuangzhou Regenerative Medicine and Health Guangdong Laboratory · CNGuangzhou Women and Children Medical Center · CNNational Medical Products Administration · CNUniversity of Washington · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ischemia/reperfusion (I/R)-induced liver injury with severe cell death is a major complication of liver transplantation. Transmembrane member 16A (TMEM16A), a component of hepatocyte Ca
Indexed as
FerroptosisLiver DiseasesReperfusion InjuryAnimalsHepatocytesInflammationIschemiaMice
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.