Evidence map›Paper›PMID 36572561›Full record

ArticleMolecules and cells2022

The Aurora Kinase Inhibitor CYC116 Promotes the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells.

Sijia Ji, Wanzhi Tu, Chenwen Huang, Ziyang Chen, Xinyue Ren, Bingqing He, Xiaoyan Ding, Yuelei Chen, Xin Xie

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules and cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sijia JiSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID https://orcid.org/0000-0001-8181-5137
Wanzhi TuSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID https://orcid.org/0000-0003-3169-6250
Chenwen HuangState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID https://orcid.org/0000-0002-9099-6715
Ziyang ChenState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID https://orcid.org/0000-0003-2270-9558
Xinyue RenState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID https://orcid.org/0000-0003-3632-7155
Bingqing HeSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID https://orcid.org/0000-0003-4928-5601
Xiaoyan DingStem Cell Bank/Stem Cell Core Facility, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.ORCID https://orcid.org/0000-0003-4698-4829
Yuelei ChenStem Cell Bank/Stem Cell Core Facility, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.ORCID https://orcid.org/0000-0002-2200-6652
Xin XieSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID https://orcid.org/0000-0003-2314-4800
ShanghaiTech University · CNShanghai Institute of Materia Medica · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have great potential in applications such as regenerative medicine, cardiac disease modeling, and

Indexed as

Induced Pluripotent Stem CellsPluripotent Stem CellsCell DifferentiationHumansMyocytes, CardiacPyrimidinesThiazoles4-methyl-5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)thiazol-2-aminePyrimidinesThiazolesAurora kinase inhibitorcardiomyocyte differentiationcell cyclehuman pluripotent stem cellmaturation

Identifiers

PMID36572561
PMCPMC9794550
OpenAlexW4312218351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.