ArticleBMJ open2022
Status of cognitive frailty in elderly patients with chronic kidney disease and construction of a risk prediction model: a cross-sectional study.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Cognitive frailty risk prediction models in patients with chronic kidney disease in China: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Risk prediction models for cognitive impairment in patients with chronic kidney disease: a systematic review.Frontiers in public health · 2026Pooled it
- The risk prediction models for cognitive frailty in the older people in China: a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- Prevalence and related factors of cognitive frailty in diabetic patients in China: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Associations of malnutrition and hydration status with cognitive frailty in older adults.European geriatric medicine · 2026Article
- Predicting cognitive frailty in older adults: an explainable machine learning model integrating radiomics and clinical features.BMC medical informatics and decision making · 2026Article
- Latent Profile Analysis of Illness Perception and Its Association with Fear of Progression in Chronic Kidney Disease.International journal of general medicine · 2026Article
- Bayesian Analysis of Frailty Risk Factors in Chronic Kidney Disease: A Nationwide Cross-Sectional Survey.Health science reports · 2026Article
- Advanced Stress Echocardiography with Cardiopulmonary Exercise Testing After Myocardial Infarction.Journal of functional morphology and kinesiology · 2025Article
- The effect of cognitive reserve on the risk of cognitive frailty in older patients receiving maintenance hemodialysis: a cross-sectional study.European geriatric medicine · 2025Article
- Development of a Lasso-Nomogram-Based Risk Prediction Model for Cognitive Frailty in Elderly MHD Patients.Neuropsychiatric disease and treatment · 2025Article
- Adverse clinical outcomes and associated factors among older adults undergoing hemodialysis in Brazil: A single-center experience.PloS one · 2025Article
- Association between depression symptoms and cognitive frailty in chronic kidney disease patients: a cross-sectional study.Frontiers in psychiatry · 2025Article
- Unraveling of Molecular Mechanisms of Cognitive Frailty in Chronic Kidney Disease: How Exercise Makes a Difference.Journal of clinical medicine · 2024Review
- Biomarkers of chronic kidney disease in older individuals: navigating complexity in diagnosis.Frontiers in medicine · 2024Review
- Risk factors analysis of cognitive frailty among geriatric adults in nursing homes based on logistic regression and decision tree modeling.Frontiers in aging neuroscience · 2024Article
- Correlation between the Cognitive Status (SIRT1) and the Metabolic Function in Geriatric Patients Using the Indonesian Version of the Montreal Cognitive Assessment (MoCA-INA).Geriatrics (Basel, Switzerland) · 2023Article
- Development and Validation of a Risk Prediction Model for Frailty in Patients with Chronic Diseases.Gerontology & geriatric medicineArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the risk factors of cognitive frailty in elderly patients with chronic kidney disease (CKD), and to establish an artificial neural network (ANN) model.
designA cross-sectional design.
settingTwo tertiary hospitals in southern China.
participants425 elderly patients aged ≥60 years with CKD.
methodsData were collected via questionnaire investigation, anthropometric measurements, laboratory tests and electronic medical records. The 425 samples were randomly divided into a training set, test set and validation set at a ratio of 5:3:2. Variables were screened by univariate and multivariate logistic regression analyses, then an ANN model was constructed. The accuracy, specificity, sensitivity, receiver operating characteristic (ROC) curve and area under the ROC curve (AUC) were used to evaluate the predictive power of the model.
resultsBarthel Index (BI) score, albumin, education level, 15-item Geriatric Depression Scale score and Social Support Rating Scale score were the factors influencing the occurrence of cognitive frailty (p<0.05). Among them, BI score was the most important factor determining cognitive frailty, with an importance index of 0.30. The accuracy, specificity and sensitivity of the ANN model were 86.36%, 88.61% and 80.65%, respectively, and the AUC of the constructed ANN model was 0.913.
conclusionThe ANN model constructed in this study has good predictive ability, and can provide a reference tool for clinical nursing staff in the early prediction of cognitive frailty in a high-risk population.
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