Evidence map›Paper›PMID 36572374›Full record

ArticleResuscitation2023

Methods for calculating ventilation rates during resuscitation from out-of-hospital cardiac arrest.

Henry E Wang, Xabier Jaureguibeitia, Elisabete Aramendi, Michelle Nassal, Ashish Panchal, Erik Alonso, Graham Nichol, Tom Aufderheide, Mohamud R Daya, Jestin Carlson and 1 more

Abstract read
In one paragraph

Article in Resuscitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Contemporary issues in pediatric prehospital airway management.Expert review of respiratory medicine · 2026
    Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Henry E WangThe Ohio State University, USA. Electronic address: henry.wang@osumc.edu.
Xabier JaureguibeitiaUniversity of the Basque Country, Spain. Electronic address: xabier.jaureguibeitia@ehu.eus.
Elisabete AramendiUniversity of the Basque Country, Spain. Electronic address: elisabete.aramendi@ehu.eus.
Michelle NassalThe Ohio State University, USA. Electronic address: Michelle.Nassal@osumc.edu.
Ashish PanchalThe Ohio State University, USA. Electronic address: Ashish.Panchal@osumc.edu.
Erik AlonsoUniversity of the Basque Country, Spain. Electronic address: erik.alonso@ehu.eus.
Graham NicholUniversity of Washington, USA. Electronic address: nichol@uw.edu.
Tom AufderheideMedical College of Wisconsin, USA. Electronic address: taufderh@mcw.edu.
Mohamud R DayaOregon Health and Science University, USA. Electronic address: dayam@ohsu.edu.
Jestin CarlsonUniversity of Pittsburgh, USA. Electronic address: jcarlson@usacs.com.
Ahamed IdrisUniversity of Texas Southwestern Medical Center, USA. Electronic address: Ahamed.Idris@utsouthwestern.edu.

Funding

Pragmatic Trial of Airway Management in Out-of-Hospital Cardiac ArrestUH3HL125163 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KERBY, JEFFREY D, WANG, HENRY E. · 2015 to 2018
$2.7M
Pragmatic Trial of Airway Management in Out-of-Hospital Cardiac ArrestUH2HL125163 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, HENRY E. · 2014 to 2014
$481k
NHLBI NIH HHS UH2 HL125163NHLBI NIH HHS UH3 HL125163
6 · The paper itself

Abstract

objectiveVentilation control is important during resuscitation from out-of-hospital cardiac arrest (OHCA). We compared different methods for calculating ventilation rates (VR) during OHCA.

methodsWe analyzed data from the Pragmatic Airway Resuscitation Trial, identifying ventilations through capnogram recordings. We determined VR by: 1) counting the number of breaths within a time epoch ("counted" VR), and 2) calculating the mean of the inverse of measured time between breaths within a time epoch ("measured" VR). We repeated the VR estimates using different time epochs (10, 20, 30, 60 sec). We defined hypo- and hyperventilation as VR <6 and >12 breaths/min, respectively. We assessed differences in estimated hypo- and hyperventilation with each VR measurement technique.

resultsOf 3,004 patients, data were available for 1,010. With the counted method, total hypoventilation increased with longer time epochs ([10-s epoch: 75 sec hypoventilation] to [60-s epoch: 97 sec hypoventilation]). However, with the measured method, total hypoventilation decreased with longer time epochs ([10-s epoch: 223 sec hypoventilation] to [60-s epoch: 150 sec hypoventilation]). With the counted method, the total duration of hyperventilation decreased with longer time epochs ([10-s epochs: 35 sec hyperventilation] to [60-s epoch: 0 sec hyperventilation]). With the measured method, total hyperventilation decreased with longer time epochs ([10-s epoch: 78 sec hyperventilation] to [60-s epoch: 0 sec hyperventilation]). Differences between the measured and counted estimates were smallest with a 60-s time epoch.

conclusionsQuantifications of hypo- and hyperventilation vary with the applied measurement methods. Measurement methods are important when characterizing ventilation rates in OHCA.

Indexed as

Cardiopulmonary ResuscitationOut-of-Hospital Cardiac ArrestHumansHyperventilationHypoventilationAirway managementCardiopulmonary arrestEmergency medical servicesIntubationVentilation

Identifiers

PMID36572374
PMCPMC12247125

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.