Evidence map›Paper›PMID 36571780›Full record

ArticleAge and ageing2022

Use of prescription benzodiazepines and related drugs in family caregivers: a nation-wide register-based study.

Tuija M Mikkola, Minna Mänty, Hannu Kautiainen, Mikaela B von Bonsdorff, Hannu Koponen, Teppo Kröger, Johan G Eriksson

Open access · hybridAbstract read
In one paragraph

Article in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Tuija M MikkolaFolkhälsan Research Center, Helsinki, Finland.ORCID 0000-0003-0885-2788
Minna MäntyUnit of Strategy and Research, City of Vantaa, Vantaa, Finland.
Hannu KautiainenFolkhälsan Research Center, Helsinki, Finland.
Mikaela B von BonsdorffFolkhälsan Research Center, Helsinki, Finland.
Hannu KoponenDepartment of Psychiatry, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Teppo KrögerDepartment of Social Sciences and Philosophy, University of Jyväskylä, Jyväskylä, Finland.ORCID 0000-0001-5019-6230
Johan G ErikssonFolkhälsan Research Center, Helsinki, Finland.
University of Helsinki · FIAgency for Science, Technology and Research · SGFolkhälsans Forskningscentrum · FIKuopio University Hospital · FIWestern Norway University of Applied Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundobjective indicators of sleep and mental health problems in family caregivers have rarely been reported.

objectiveto study the use of prescription benzodiazepines and related drugs (BZDRD) in Finnish family caregivers and matched controls.

designprospective follow-up in 2012-17.

settingnationwide register-linkage study. SUBJECTS: all individuals who received family caregiver's allowance in Finland in 2012 (N = 42,256; mean age 67 years; 71% women) and controls matched for age, sex and municipality of residence (N = 83,618).

methodsinformation on purchases of prescription BZDRD, including the number of defined daily doses (DDDs), between 2012 and 2017 was obtained from the Dispensations Reimbursable under the National Health Insurance Scheme register. Background information was obtained from national registers.

resultsmore caregivers than controls used BZDRD, both among women (users per 100 person-years: 17.2 versus 15.2, P < 0.001) and men (14.6 versus 11.8, P < 0.001). These differences were largely explained by hypnotic BZDRD use. There were also more long-term BZDRD users per 100 person-years among caregivers than controls, both among women (5.0 versus 4.3, P = 0.001) and men (5.3 versus 3.8, P < 0.001). Use of hypnotic BZDRD in number of DDDs was higher in caregivers than in controls, particularly among men above 50 years. Caregivers used more anxiolytic BZDRD than controls from middle age to 75 years but less in the oldest age groups.

conclusionshigher level of BZDRD use among caregivers indicates that caregivers have more sleep and mental health problems than non-caregivers. Adequate treatment of these problems and support for caregiving should be ensured for caregivers.

Indexed as

CaregiversHypnotics and SedativesAgedBenzodiazepinesFemaleHumansMalePrescriptionsProspective StudiesBenzodiazepinesHypnotics and Sedativesageinginformal caregivinginsomniamental disordersolder peoplepsychoactive drugs

Identifiers

PMID36571780
PMCPMC9792078
OpenAlexW4312220009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.