ArticleAge and ageing2022
The impact of frailty on patient-reported outcomes following hip and knee arthroplasty.
Article in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06866678 (Can the Frailty Score Independently Predict Surgical Risk and Postoperative Morbidity in Patients With Colorectal Cancer?), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can the Frailty Score Independently Predict Surgical Risk and Postoperative Morbidity in Patients With Colorectal Cancer?
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- The impact of retaining the femoral stem in revision total hip arthroplasty: a systematic review, meta-analysis, and meta-regression.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Trial
- A 15-year evaluation of two total knee arthroplasty designs : similar patient-reported outcomes and survivorship but divergent patellofemoral and radiological outcomes.Bone & joint open · 2026Article
- Nutritional disorders have adverse effect on clinical outcomes and may increase healthcare costs following hip and knee arthroplasty-A systematic review.Journal of experimental orthopaedics · 2026Review
- Frailty and Sarcopenia as Predictors of Functional Recovery After Total Hip and Knee Arthroplasty: A Narrative Review.Journal of clinical medicine · 2026Review
- Impact of preoperative education on early outcomes following hip and knee arthroplasty : a 21,000-patient multicentre NHS analysis.Bone & joint open · 2026Article
- Multimodal prehabilitation for frail older adults having hip or knee replacement: a qualitative exploratory study of barriers and facilitators.BMC musculoskeletal disorders · 2026Article
- Outcome measures in prehabilitation interventions for total hip and knee arthroplasty: A scoping review.Clinical rehabilitation · 2026Article
- Achieved discharge outcome targets in patient-reported outcome measures after lower limb arthroplasty.Bone & joint research · 2025Article
- Frailty: An overlooked red flag in sports surgery.Journal of experimental orthopaedics · 2025Article
- No meaningful clinical differences in patient reported outcome scores for Native Hawaiian/Pacific Islanders following knee or hip arthroplasty.Archives of orthopaedic and trauma surgery · 2025Article
- A longitudinal study on the correlation between postoperative complications and frailty in older patients with joint disorders.Aging clinical and experimental research · 2025Article
- Frailty indices based on routinely collected data: a scoping review.The Journal of frailty & aging · 2025Article
- Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging.Aging cell · 2024Review
- Concomitant malnutrition and frailty are significant risk factors for poor outcome following two-stage revision for chronic periprosthetic joint infection.Journal of orthopaedic surgery and research · 2023Article
- Review
- Prehabilitation for frail patients undergoing total hip or knee replacement: protocol for the Joint PREP feasibility randomised controlled trial.Pilot and feasibility studies · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
aimto determine the impact of frailty on patient-reported outcomes following hip and knee arthroplasty.
methodswe used linked primary and secondary care electronic health records. Frailty was assessed using the electronic frailty index (categorised: fit, mild, moderate, severe frailty). We determined the association between frailty category and post-operative Oxford hip/knee score (OHS/OKS) using Tobit regression. We calculated the proportion of patients in each frailty category who achieved the minimally important change (MIC) in OHS (≥8 points) and OKS (≥7 points) and the proportion who reported a successful outcome (hip/knee problems either 'much better' or 'a little better' following surgery).
resultsAbout 42,512 people who had a hip arthroplasty and 49,208 who had a knee arthroplasty contributed data. In a Tobit model adjusted for pre-operative OHS/OKS, age, sex and quintile of index of multiple deprivation, increasing frailty was associated with decreasing post-operative OHS and OKS, respectively, β-coefficient (95% CI) in severely frail versus fit, -6.97 (-7.44, -6.49) and - 5.88 (-6.28, -5.47). The proportion of people who achieved the MIC in OHS and OKS, respectively, decreased from 92 and 86% among fit individuals to 84 and 78% among those with severe frailty. Patient-reported success following hip and knee arthroplasty, respectively, decreased from 97 and 93% among fit individuals to 90 and 83% among those with severe frailty.
conclusionfrailty adversely impacts on patient-reported outcomes following hip and knee arthroplasty. However, even among those with severe frailty, the large majority achieved the MIC in OHS/OKS and reported a successful outcome.
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Registered trials
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