ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Chronic physical conditions, physical multimorbidity, and quality of life among adults aged ≥ 50 years from six low- and middle-income countries.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
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- Multiple Chronic Conditions and Multimorbidity Among Older Adults in Southern Albania: Distribution and Impact on Care Needs, Medication Adherence, and Quality of Life.Healthcare (Basel, Switzerland) · 2026Article
- Multidimensional Determinants of Food and Nutritional Insecurity Among Older Adults: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Patient Perspectives of Early Interventions for Healthy Ageing in General Practice: A Qualitative Study.Australasian journal on ageing · 2026Article
- One-year follow-up of survival and health-related quality of life in patients with medical conditions admitted acutely to hospital in Malawi and Tanzania.Anaesthesia · 2026Article
- Quality of life for middle and older aged people with chronic conditions in primary care: a cross-sectional study.BMC primary care · 2026Observational
- Multimorbidity Management: A Scoping Review of Interventions and Health Outcomes.International journal of environmental research and public health · 2025Article
- Perceived neighborhood safety, crime exposure, and chronic diseases among older Indians: The role of functional disabilities.PLOS global public health · 2025Article
- Ageing, multimorbidity, and quality of life: a mediation analysis using longitudinal ageing study in India.Frontiers in public health · 2025Article
- Modeling the spectrum and determinants of multimorbidity risk among older adults in India.PloS one · 2025Article
- Phenome-wide diagnostic comparison among suicide deaths and living individuals with chronic pain diagnoses.BMC medicine · 2024Article
- Sleep problems and their predictors in community-dwelling older adults with diabetes in India: Evidence from the Longitudinal Ageing Study in India.Sleep medicine: X · 2024Article
- Botulinum toxin in the rehabilitation of painful syndromes: multiperspective literature analysis, lexical analysis and systematic review of randomized controlled trials.European journal of translational myology · 2024Article
- Multimorbidity patterns and health-related quality of life among community-dwelling older adults: evidence from a rural town in Suzhou, China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Exploring the Influence of Social Class and Sex on Self-Reported Health: Insights from a Representative Population-Based Study.Life (Basel, Switzerland) · 2024Article
- Health-Related Quality of Life among Older Adults with Dementia Living in Vietnamese Nursing Homes.International journal of environmental research and public health · 2024Article
- An interpretative phenomenological analysis of the lived experience of people with multimorbidity in low- and middle-income countries.BMJ global health · 2024Article
- Decomposing the rural-urban differences in depression among multimorbid older patients in India: evidence from a cross-sectional study.BMC psychiatry · 2024Article
- Illness Intrusiveness, Perceived Control, and Quality of Life in Older Adults with Arthritis and Multimorbidity.Clinical gerontologistArticle
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14 authors.
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Abstract
purposeMultimorbidity (i.e., ≥ 2 chronic conditions) poses a challenge for health systems and governments, globally. Several studies have found inverse associations between multimorbidity and quality of life (QoL). However, there is a paucity of studies from low- and middle-income countries (LMICs), especially among the older population, as well as studies examining mediating factors in this association. Thus, the present study aimed to explore the associations, and mediating factors, between multimorbidity and QoL among older adults in LMICs.
methodsCross-sectional nationally representative data from the Study on Global Ageing and Adult Health were analyzed. A total of 11 chronic conditions were assessed. QoL was assessed with the 8-item WHO QoL instrument (range 0-100) with higher scores representing better QoL. Multivariable linear regression and mediation analyses were conducted to assess associations.
resultsThe final sample consisted of 34,129 adults aged ≥ 50 years [mean (SD) age 62.4 (16.0) years; age range 50-114 years; 52.0% females]. Compared to no chronic conditions, 2 (b-coefficient - 5.89; 95% CI - 6.83, - 4.95), 3 (- 8.35; - 9.63, - 7.06), 4 (- 10.87; - 12.37, - 9.36), and ≥ 5 (- 13.48; - 15.91, - 11.06) chronic conditions were significantly associated with lower QoL, dose-dependently. The mediation analysis showed that mobility (47.9%) explained the largest proportion of the association between multimorbidity and QoL, followed by pain/discomfort (43.5%), sleep/energy (35.0%), negative affect (31.9%), cognition (20.2%), self-care (17.0%), and interpersonal activities (12.0%).
conclusionA greater number of chronic conditions was associated with lower QoL dose-dependently among older adults in LMICs. Public health and medical practitioners should aim to address the identified mediators to improve QoL in patients with multimorbidity.
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