Evidence map›Paper›PMID 36571623›Full record

ArticleSocial psychiatry and psychiatric epidemiology2023

Comparing treatment delays and pathways to early intervention services for psychosis in urban settings in India and Canada.

Kathleen MacDonald, Greeshma Mohan, Nicole Pawliuk, Ridha Joober, Ramachandran Padmavati, Thara Rangaswamy, Ashok Malla, Srividya N Iyer

Open access · greenAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Kathleen MacDonald *Prevention and Early Intervention Program for Psychosis (PEPP-Montreal), Douglas Mental Health University Institute, Wilson Pavilion, 6875 Boulevard LaSalle, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0002-9782-0368
Greeshma Mohan *Schizophrenia Research Foundation (SCARF), R-7A North Main Road, Anna Nagar West Extension, Chennai, Tamil Nadu, 600 101, India.ORCID http://orcid.org/0000-0002-6322-5413
Nicole PawliukPrevention and Early Intervention Program for Psychosis (PEPP-Montreal), Douglas Mental Health University Institute, Wilson Pavilion, 6875 Boulevard LaSalle, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0002-9544-4565
Ridha JooberPrevention and Early Intervention Program for Psychosis (PEPP-Montreal), Douglas Mental Health University Institute, Wilson Pavilion, 6875 Boulevard LaSalle, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0003-3492-807X
Ramachandran PadmavatiSchizophrenia Research Foundation (SCARF), R-7A North Main Road, Anna Nagar West Extension, Chennai, Tamil Nadu, 600 101, India.ORCID http://orcid.org/0000-0002-0380-8617
Thara RangaswamySchizophrenia Research Foundation (SCARF), R-7A North Main Road, Anna Nagar West Extension, Chennai, Tamil Nadu, 600 101, India.ORCID http://orcid.org/0000-0001-6813-066X
Ashok Malla *Prevention and Early Intervention Program for Psychosis (PEPP-Montreal), Douglas Mental Health University Institute, Wilson Pavilion, 6875 Boulevard LaSalle, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0002-5863-4191
Srividya N Iyer *Prevention and Early Intervention Program for Psychosis (PEPP-Montreal), Douglas Mental Health University Institute, Wilson Pavilion, 6875 Boulevard LaSalle, Montreal, QC, H4H 1R3, Canada. srividya.iyer@mcgill.ca.ORCID http://orcid.org/0000-0001-5367-9086
Douglas Mental Health University Institute · CASchizophrenia Research Foundation · IN

Funding

Early Psychosis in India and Canada: Investigating outcomes and family factorsR01MH093303 · NIMH · MCGILL UNIVERSITY · PI MALLA, ASHOK · 2012 to 2016
$2.3M
CIHR Salary AwardFonds de recherche du Québec Santé, Canada Doctoral awardFonds de recherche du Québec-Santé, Canada Salary AwardNIH HHS 5R01MH093303-05NIHR, United Kingdom Doctoral FundingNIMH NIH HHS R01 MH093303TATA Trusts, India Doctoral funding
6 · The paper itself

Abstract

introductionAlthough extensively studied in high-income countries (HICs) and less so in low- and middle-income countries (LMICs), pathways to care and treatment delays in early psychosis have not been compared across contexts. We compared pathways to early intervention for psychosis in an HIC (Montreal, Canada) and an LMIC (Chennai, India). We hypothesised that the duration of untreated psychosis (DUP) would be longer in Chennai.

methodsThe number of contacts preceding early intervention, referral sources, first contacts, and DUP and its referral and help-seeking components of first-episode psychosis patients at both sites were similarly measured and compared using chi-square analyses and t tests/one-way ANOVAs.

resultsOverall and help-seeking DUPs of Chennai (N = 168) and Montreal (N = 165) participants were not significantly different. However, Chennai patients had shorter referral DUPs [mean = 12.0 ± 34.1 weeks vs. Montreal mean = 13.2 ± 28.7 weeks; t(302.57) = 4.40; p < 0.001] as the early intervention service was the first contact for 44% of them (vs. 5% in Montreal). Faith healers comprised 25% of first contacts in Chennai. Those seeing faith healers had significantly shorter help-seeking but longer referral DUPs. As predicted, most (93%) Montreal referrals came from medical sources. Those seeing psychologists/counsellors/social workers as their first contact had longer DUPs.

conclusionDifferences in cultural views about mental illnesses and organizational structures shape pathways to care and their associations with treatment delays across contexts. Both formal and informal sources need to be targeted to reduce delays. Early intervention services being the first portal where help is sought can reduce DUP especially if accessed early on in the illness course.

Indexed as

Psychotic DisordersTime-to-TreatmentCanadaEarly Intervention, EducationalHumansIndiaCross-culturalDuration of untreated psychosisEarly interventionLMICsPathways to carePsychosis

Identifiers

PMID36571623
PMCPMC10088896
OpenAlexW4312195320

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.