Evidence map›Paper›PMID 36570850›Full record

ArticleFrontiers in neuroscience2022

Luminance white noise electroretinograms (wnERGs) in mice.

Nina Stallwitz, Anneka Joachimsthaler, Jan Kremers

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The interaction between the ERG responses to sinusoidal modulation and flashes in mice.Documenta ophthalmologica. Advances in ophthalmology · 2026
    Article
  2. Article
  3. Single opsin driven white noise ERGs in mice.Frontiers in neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nina StallwitzSection for Retinal Physiology, Department of Ophthalmology, University Hospital Erlangen, Erlangen, Germany.
Anneka JoachimsthalerSection for Retinal Physiology, Department of Ophthalmology, University Hospital Erlangen, Erlangen, Germany.
Jan KremersSection for Retinal Physiology, Department of Ophthalmology, University Hospital Erlangen, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To record and analyse electroretinograms (ERGs) to luminance stimuli with white noise temporal profiles in mice. White noise stimuli are expected to keep the retina in a physiologically more natural state than, e.g., flashes. The influence of mean luminance (ML) was studied. Methods: Electroretinograms to luminance temporal white noise (TWN) modulation (wnERGs) were measured. The white noise stimuli contained all frequencies up to 20 Hz with equal amplitudes and random phases. Responses were recorded at 7 MLs between -0.7 and 1.2 log cd/m Results: The amplitudes of the initial (a-wave-like) trough of the IRFs increased with increasing ML. The following positive (b-wave-like) peak showed a minimum at -0.4 log cd/m Conclusion: White noise electroretinograms can be reliably recorded in mice with luminance stimuli. IRFs resemble flash ERGs superficially, but they offer a novel procedure to study retinal physiology. New components can be described in the IRFs. The wnERGs are either rod- or cone-driven with little overlap.

Indexed as

electroretinogram (ERG)ERG generating mechanismsimpulse response function (IRF)micemodulation transfer function (MTF)temporal white noise (TWN)white noise electroretinogram (wnERG)

Identifiers

PMID36570850
PMCPMC9780692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.