Evidence map›Paper›PMID 36570617›Full record

ArticleBeilstein journal of nanotechnology2022

Frequency-dependent nanomechanical profiling for medical diagnosis.

Santiago D Solares, Alexander X Cartagena-Rivera

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. High-Throughput Nanorheology of Living Cells Powered by Supervised Machine Learning.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Santiago D SolaresDepartment of Mechanical and Aerospace Engineering, The George Washington University, School of Engineering and Applied Science, Washington, District of Columbia, USA.ORCID https://orcid.org/0000-0003-0895-8160
Alexander X Cartagena-RiveraSection on Mechanobiology, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0001-6227-2499
George Washington University · USNational Institutes of Health · US

Funding

MechanobiologyZIAEB000094 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI CARTAGENA-RIVERA, ALEXANDER · 2020 to 2025
$6.0M
Intramural NIH HHS ZIA EB000094
6 · The paper itself

Abstract

Atomic force microscopy (AFM), developed in the early 1980s, has become a powerful characterization tool in micro- and nanoscale science. In the early 1990s, its relevance within biology and medicine research became evident, although its incorporation into healthcare applications remains relatively limited. Here, we briefly explore the reasons for this low level of technological adoption. We also propose a path forward for the incorporation of frequency-dependent nanomechanical measurements into integrated healthcare strategies that link routine AFM measurements with computer analysis, real-time communication with healthcare providers, and medical databases. This approach would be appropriate for diseases such as cancer, lupus, arteriosclerosis and arthritis, among others, which bring about significant mechanical changes in the affected tissues.

Indexed as

atomic force microscopyhealthcaremechanical propertiesmechanobiologymedical diagnosis

Identifiers

PMID36570617
PMCPMC9749500
OpenAlexW4311970558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.