ReviewFrontiers in aging neuroscience2022
Post-COVID-19 human memory impairment: A PRISMA-based systematic review of evidence from brain imaging studies.
Review in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Neurexin dysfunction in neurodevelopmental and neuropsychiatric disorders: a PRIMSA-based systematic review through iPSC and animal models.Frontiers in behavioral neuroscience · 2024Pooled it
- New Strategies for the Prevention and Therapy of Alzheimer's Disease Based on Stimulation of Brain Drainage and Lymphatic Clearance.International journal of molecular sciences · 2026Review
- Post-COVID conditions: co-occurrence of symptoms and challenges for comprehensive care.Revista da Escola de Enfermagem da U S P · 2026Observational
- Treatment experiences, preferences, and expectations for cognitive impairments in long COVID among Chinese young and older adults: a constructivist grounded theory study.BMC medicine · 2025Article
- Neuroimmune pathophysiology of long COVID.Psychiatry and clinical neurosciences · 2025Review
- Cognitive Decline in Patients With Trigeminal Neuralgia: A Resting-State fMRI Study.Brain and behavior · 2025Article
- The relationship between cognitive function and neuropsychiatric disorders with quantitative electroencephalogram (qEEG) on long COVID syndrome patients.Brain, behavior, & immunity - health · 2025Article
- Health Resort Treatment Mitigates Neuropsychiatric Symptoms in Long COVID Patients: A Retrospective Study.Healthcare (Basel, Switzerland) · 2025Article
- Article
- Infarct volume as a predictor and therapeutic target in post-stroke cognitive impairment.Frontiers in medicine · 2025Review
- Review
- Characterization of cognitive symptoms in post COVID-19 patients.European archives of psychiatry and clinical neuroscience · 2024Article
- Evaluation of microstructural brain changes in post-coronavirus disease 2019 (COVID-19) patients with neurological symptoms: a cross-sectional study.Quantitative imaging in medicine and surgery · 2024Article
- Advanced magnetic resonance neuroimaging techniques: feasibility and applications in long or post-COVID-19 syndrome - a review.Annals of medicine and surgery (2012) · 2024Review
- Cognitive function and quantitative electroencephalogram analysis in subjects recovered from COVID-19 infection.BMC neurology · 2024Article
- Understanding Post-COVID-19: Mechanisms, Neurological Complications, Current Treatments, and Emerging Therapies.International journal of general medicine · 2024Article
- Article
- Immunoglobulin A as a Key Immunological Molecular Signature of Post-COVID-19 Conditions.Viruses · 2023Article
- Long COVID prevalence and impact on quality of life 2 years after acute COVID-19.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many people with coronavirus disease 2019 (COVID-19) report varying degrees of memory impairment. Neuroimaging techniques such as MRI and PET have been utilized to shed light on how COVID-19 affects brain function in humans, including memory dysfunction. In this PRISMA-based systematic review, we compared and summarized the current literature looking at the relationship between COVID-19-induced neuropathological changes by neuroimaging scans and memory symptoms experienced by patients who recovered from COVID-19. Overall, this review suggests a correlational trend between structural abnormalities (e.g., cortical atrophy and white matter hyperintensities) or functional abnormalities (e.g., hypometabolism) in a wide range of brain regions (particularly in the frontal, parietal and temporal regions) and memory impairments in COVID-19 survivors, although a causal relationship between them remains elusive in the absence of sufficient caution. Further longitudinal investigations, particularly controlled studies combined with correlational analyses, are needed to provide additional evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.