Evidence map›Paper›PMID 36570471›Full record

ArticlePhotoacoustics2023

Size-tunable ICG-based contrast agent platform for targeted near-infrared photoacoustic imaging.

Shrishti Singh, Giovanni Giammanco, Chih-Hsiang Hu, Joshua Bush, Leandro Soto Cordova, Dylan J Lawrence, Jeffrey L Moran, Parag V Chitnis, Remi Veneziano

Open access · goldAbstract read
In one paragraph

Article in Photoacoustics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

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  12. Bornite (CuPhotoacoustics · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. An Indocyanine Green-Based Nanoprobe for In Vivo Detection of Cellular Senescence.Angewandte Chemie (International ed. in English) · 2024
    Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shrishti SinghDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
Giovanni GiammancoDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
Chih-Hsiang HuDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
Joshua BushDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
Leandro Soto CordovaDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
Dylan J LawrencePhotoSound Technologies Inc., Houston, TX 77036, USA.
Jeffrey L MoranDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
Parag V ChitnisDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
Remi VenezianoDepartment of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
George Mason University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-infrared photoacoustic imaging (NIR-PAI) combines the advantages of optical and ultrasound imaging to provide anatomical and functional information of tissues with high resolution. Although NIR-PAI is promising, its widespread use is hindered by the limited availability of NIR contrast agents. J-aggregates (JA) made of indocyanine green dye (ICG) represents an attractive class of biocompatible contrast agents for PAI. Here, we present a facile synthesis method that combines ICG and ICG-azide dyes for producing contrast agents with tunable size down to 230 nm and direct functionalization with targeting moieties. The ICG-JA platform has a detectable PA signal

Indexed as

Contrast agentImaging probeIndocyanine green (ICG)J-aggregates (JA)Photoacoustic imaging (PAI)

Identifiers

PMID36570471
PMCPMC9772562
OpenAlexW4311537945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.