Evidence map›Paper›PMID 36570354›Full record

ArticleInternational journal of organ transplantation medicine2021

Importance of miR-UL-148D Expression Pattern in Cytomegalovirus Infected Transplant Patients.

M Golshan, R Yaghobi, B Geramizadeh, A Afshari, J Roozbeh, S A Malek-Hosseini

Open access · greenAbstract read
In one paragraph

Article in International journal of organ transplantation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

M GolshanDepartment of Molecular Genetics, Fars Science and Research Branch, Islamic Azad University, Marvdasht, Iran.
R YaghobiTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
B GeramizadehTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
A AfshariShiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
J RoozbehShiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
S A Malek-HosseiniShiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRIslamic Azad University, Marvdasht · IRSina Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: MicroRNAs (miRNAs) are endogenous, 18-22 nucleotide non-coding RNA molecules. Human cytomegalovirus (HCMV) is a ubiquitous and particular herpes virus that encodes miRNAs, which increases gradually in the presence of infection. One of the important viral miRNAs is HCMV-miRUL-148D, which plays a role in establishing and maintaining viral latency. Objective: The current study aimed to evaluate the expression levels of HCMV-miRUL-148D in active and inactive HCMV infected transplant patient groups compared to healthy individuals. Methods: Total RNA was extracted from blood samples of 60 solid organ transplant patients and 30healthy controls. In-house SYBR Green Real-Time PCR evaluated the expression levels of studied miRNAand gene. Results: The expression level of the Conclusion: Increased miRUL-148D expression level in the inactive HCMV-infected transplant patients indicates the potential role of this miRUL-148D as a biomarker of the HCMV latent stage.

Indexed as

Human CytomegalovirusmiRNAmiRUL-148DTransplantation

Identifiers

PMID36570354
PMCPMC9758995
OpenAlexW4312209994

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.