Evidence map›Paper›PMID 36570353›Full record

ArticleInternational journal of organ transplantation medicine2021

Reversible Calcineurin Inhibitor-associated Sensorimotor Polyneuropathy in a Lung Transplant Recipient: A Case Report.

T Antychin, J A Zarowski, V Verplancke, J M H Hendriks, S K Yogeswaran, P Lauwers, K Lamote, J M Kwakkel-van Erp

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PubMed Full text at PMC
In one paragraph

Article in International journal of organ transplantation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

T AntychinDepartment of Pulmonology, Antwerp University Hospital, Edegem, Belgium.
J A ZarowskiDepartment of Pulmonology, Antwerp University Hospital, Edegem, Belgium.
V VerplanckeDepartment of Pulmonology, Antwerp University Hospital, Edegem, Belgium.
J M H HendriksDepartment of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium.
S K YogeswaranDepartment of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium.
P LauwersDepartment of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium.
K LamoteLaboratory of Experimental Medicine and Pediatrics, University of Antwerp, Wilrijk, Belgium.
J M Kwakkel-van ErpDepartment of Pulmonology, Antwerp University Hospital, Edegem, Belgium.
University of Antwerp · BEAntwerp University Hospital · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcineurin inhibitors (CNIs) are regarded as a corner stone in immunosuppressive therapy after solid organ transplantation. However, neurotoxicity is a common side effect of CNIs, resulting in a wide range of neurological symptoms such as headache, tremor and seizures. In this case report, we describe a patient who developed severe motor and sensory neuron dysfunction related to CNIs after bilateral lung transplantation, which resolved after halting CNI and switching to a mammalian Target of Rapamycin-inhibitor.

Indexed as

Calcineurin inhibitorsLung transplantationmTOR-inhibitorReversible neuropathy

Identifiers

PMID36570353
PMCPMC9758996
OpenAlexW4312211936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.