Evidence map›Paper›PMID 36570128›Full record

ArticleFrontiers in nutrition2022

Intake of

Eiji Kobatake, Yoshitaka Iwama, Toshinobu Arai, Nobuhiko Shioya, Mai Kise, Toshihide Kabuki

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Nutrients · 2023
    Trial
  4. DNA fromMicroorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eiji KobatakeMilk Science Research Institute, MEGMILK SNOW BRAND Co., Ltd., Saitama, Japan.
Yoshitaka IwamaNihonbashi Cardiology Clinic, Tokyo, Japan.
Toshinobu AraiResearch and Development Planning Department, MEGMILK SNOW BRAND Co., Ltd., Tokyo, Japan.
Nobuhiko ShioyaKSO Corporation, Tokyo, Japan.
Mai KiseProducts Development Department, MEGMILK SNOW BRAND Co., Ltd., Saitama, Japan.
Toshihide KabukiMilk Science Research Institute, MEGMILK SNOW BRAND Co., Ltd., Saitama, Japan.
Megmilk Snow Brand (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Materials and methods: In this randomized, double-blind, placebo-controlled, parallel-group comparative study, Japanese individuals aged 20-64 years were recruited. A total of 200 participants were randomly divided into two groups by an independent controller (LG2055 and placebo groups; 100 participants per group). Drinkable yogurts containing LG2055 or lacking LG2055 (placebo) were used as test samples. The participants ingested one bottle of the test sample once a day for 12 weeks. A daily physical health questionnaire survey (about common cold symptoms) was performed as the primary outcome, and immunological and oxidative stress markers in saliva and serum were evaluated as secondary outcomes. Results: In total, 198 participants completed the scheduled intake of the test samples, and five participants were excluded from the final analysis. Consequently, 193 participants (LG2055 group, Conclusion: Our study revealed that intake of LG2055 decreased common cold symptoms and improved immune parameters in healthy adults. This suggests that LG2055 contributes to the maintenance of physical conditions by improving the host immune system. Clinical trial registration: [https://www.umin.ac.jp/ctr/index.htm], identifier [UMIN000045901].

Indexed as

clinical studycommon coldLactobacillus paragasseri SBT2055oxidative stressprobioticssalivary sIgAsubjective symptoms

Identifiers

PMID36570128
PMCPMC9773393
OpenAlexW4311867540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.