Evidence map›Paper›PMID 36570094›Full record

ArticleInformatics in medicine unlocked2022

Computer-aided identification of potential inhibitors against

Samuel K Kwofie, Seth O Asiedu, Russell Koranteng, Emelia Quarshie, Elvis K Tiburu, Whelton A Miller, Michael B Adinortey, Michael D Wilson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Informatics in medicine unlocked, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Samuel K KwofieDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana.
Seth O AsieduDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana.
Russell KorantengDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana.
Emelia QuarshieDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana.
Elvis K TiburuDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana.
Whelton A MillerDepartment of Medicine, Loyola University Medical Center, Maywood, IL, 60153, USA.
Michael B AdinorteyDepartment of Biochemistry, School of Biological Sciences, College of Agricultural and Natural Sciences, University of Cape Coast, Ghana.
Michael D WilsonDepartment of Parasitology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, Legon, Accra, Ghana.
University of Ghana · GHLoyola University Medical Center · USUniversity of Cape Coast · GH

Funding

Noguchi Institute Initiative for NTDs Elimination (NIINE)U19AI129916 · NIAID · NOGUCHI MEMORIAL INSTITUTE / MEDICAL RES · PI WILSON, MICHAEL D · 2017 to 2021
$1.9M
Epidemiology and molecular mechanisms of anthelminthic treatment failure in KintaR01AI099623 · NIAID · NOGUCHI MEMORIAL INSTITUTE / MEDICAL RES · PI WILSON, MICHAEL D · 2012 to 2016
$605k
NIAID NIH HHS R01 AI099623NIAID NIH HHS U19 AI129916
6 · The paper itself

Abstract

Hookworm infection is caused by the blood-feeding hookworm gastrointestinal nematodes. Its harmful effects include anemia and retarded growth and are common in the tropics. A current control method involves the mass drug administration of synthetic drugs, mainly albendazole and mebendazole. There are however concerns of low efficacy and drug resistance due to their repeated and excessive use. Although,

Indexed as

AnthelminticsMolecular dockingMolecular dynamicsNatural productsNecator americanusPharmacoinformatics

Identifiers

PMID36570094
PMCPMC9784411
OpenAlexW4225322510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.