Evidence map›Paper›PMID 36570080›Full record

ArticleACS catalysis2022

Computation-Aided Engineering of Cytochrome P450 for the Production of Pravastatin.

Mark A Ashworth, Elvira Bombino, René M de Jong, Hein J Wijma, Dick B Janssen, Kirsty J McLean, Andrew W Munro

Open access · hybridAbstract read
In one paragraph

Article in ACS catalysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Rational design of enzyme activity and enantioselectivity.Frontiers in bioengineering and biotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Mark A AshworthManchester Institute of Biotechnology, School of Chemistry, The University of Manchester, Manchester M1 7DN, United Kingdom.
Elvira BombinoDepartment of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, Groningen 9747 AG, Netherlands.ORCID https://orcid.org/0000-0002-1902-5668
René M de JongDSM Food & Beverage, Alexander Fleminglaan 1, 2613 AX Delft, the Netherlands.
Hein J WijmaDepartment of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, Groningen 9747 AG, Netherlands.ORCID https://orcid.org/0000-0003-0891-6972
Dick B JanssenDepartment of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, Groningen 9747 AG, Netherlands.ORCID https://orcid.org/0000-0002-0834-2043
Kirsty J McLeanManchester Institute of Biotechnology, School of Chemistry, The University of Manchester, Manchester M1 7DN, United Kingdom.
Andrew W MunroManchester Institute of Biotechnology, School of Chemistry, The University of Manchester, Manchester M1 7DN, United Kingdom.ORCID https://orcid.org/0000-0002-4642-180X
University of Groningen · NLUniversity of Manchester · GBDSM (Netherlands) · NLUniversity of Huddersfield · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G014329/1
6 · The paper itself

Abstract

CYP105AS1 is a cytochrome P450 from

Identifiers

PMID36570080
PMCPMC9764288
OpenAlexW4310131927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.