Evidence map›Paper›PMID 36570020›Full record

ArticleMediators of inflammation2022

MiR-181a-5p Delivered by Adipose-Derived Mesenchymal Stem Cell Exosomes Alleviates

Ren-Jing Hu, Xiao-Chun Chen, Lei Xu, Xiao-Hong Rui, Lin Wan, Jie Lu, Jun Liu, Hao Pei

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ren-Jing HuDepartment of Laboratory Medicine, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, Wuxi City, 214000 Jiangsu Province, China.
Xiao-Chun ChenDepartment of Laboratory Medicine, Taizhou Second People's Hospital, Taizhou City, 225411 Jiangsu Province, China.
Lei XuDepartment of Oral and Maxillofacial Surgery, Wuxi Stomatological Hospital, Wuxi City, 214001 Jiangsu Province, China.
Xiao-Hong RuiDepartment of Laboratory Medicine, Wuxi Fifth People's Hospital, Wuxi City, 214000 Jiangsu Province, China.
Lin WanDepartment of Laboratory Medicine, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, Wuxi City, 214000 Jiangsu Province, China.
Jie LuDepartment of Laboratory Medicine, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, Wuxi City, 214000 Jiangsu Province, China.
Jun LiuDepartment of Laboratory Medicine, Wuxi Fifth People's Hospital, Wuxi City, 214000 Jiangsu Province, China.
Hao PeiDepartment of Laboratory Medicine, Wuxi Fifth People's Hospital, Wuxi City, 214000 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-2422-8419
Wuxi People's Hospital · CNShanghai Stomatological Hospital · CNTaizhou Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aim: In this study, we aimed to explore the effect of ADSC-derived exosomal miR-181-5p on Methods: C57BL/6 mouse model was established by infection of Results: We successfully isolated the ADSCs that express positive markers CD90 and CD105 rather than CD31 and CD45. The exosomal miR-181a-5p secreted by ADSCs were internalized by BMDM and Conclusion: Consequently, we concluded that ADSC-derived exosomal miR-181a-5p alleviated

Indexed as

ExosomesLung InjuryMesenchymal Stem CellsMicroRNAsPneumoniaAnimalsKlebsiella pneumoniaeMiceMice, Inbred C57BLMicroRNAs

Identifiers

PMID36570020
PMCPMC9771653
OpenAlexW4311471829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.