Evidence map›Paper›PMID 36569912›Full record

ReviewFrontiers in immunology2022

Sex differences in Guillain Barré syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and experimental autoimmune neuritis.

Pamela A McCombe, Todd A Hardy, Robert J Nona, Judith M Greer

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Observational
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  11. [Epidemiological and clinical aspects of Guilain-Barré syndrome, 2012-2022].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pamela A McCombeCentre for Clinical Research, The University of Queensland, Brisbane, QLD, Australia.
Todd A HardyDepartment of Neurology, Concord Hospital, University of Sydney, Sydney, NSW, Australia.
Robert J NonaCentre for Clinical Research, The University of Queensland, Brisbane, QLD, Australia.
Judith M GreerCentre for Clinical Research, The University of Queensland, Brisbane, QLD, Australia.
University of Queensland · AUConcord Repatriation General Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guillain Barré syndrome (GBS) and its variants, and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP and its variants, are regarded as immune mediated neuropathies. Unlike in many autoimmune disorders, GBS and CIDP are more common in males than females. Sex is not a clear predictor of outcome. Experimental autoimmune neuritis (EAN) is an animal model of these diseases, but there are no studies of the effects of sex in EAN. The pathogenesis of GBS and CIDP involves immune response to non-protein antigens, antigen presentation through non-conventional T cells and, in CIDP with nodopathy, IgG4 antibody responses to antigens. There are some reported sex differences in some of these elements of the immune system and we speculate that these sex differences could contribute to the male predominance of these diseases, and suggest that sex differences in peripheral nerves is a topic worthy of further study.

Indexed as

Autoimmune DiseasesGuillain-Barre SyndromeNeuritis, Autoimmune, ExperimentalPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingAnimalsFemaleMaleSex Characteristicschronic inflammatory demyelinating polyradiculoneuropathyexperimental autoimmune neuritisgangliosidesGuillain Barré syndromeIgG4 antibodiessex differences

Identifiers

PMID36569912
PMCPMC9780466
OpenAlexW4311953610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.