Evidence map›Paper›PMID 36569884›Full record

ReviewFrontiers in immunology2022

The study of neural antibodies in neurology: A practical summary.

Mireya Fernández-Fournier, Laura Lacruz, Pilar Nozal, Juan Luis Chico, Antonio Tallón Barranco, Laura Otero-Ortega, Iñigo Corral, Angela Carrasco

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mireya Fernández-FournierNeuroimmunology and MS Unit, Department of Neurology, La Paz University Hospital, Neurology and Cerebrovascular Disease Group, Neuroscience Area of Hospital La Paz Institute for Health Research - IdiPAZ, Universidad Autónoma de Madrid,Madrid, Spain.
Laura LacruzNeuroimmunology and MS Unit, Department of Neurology, La Paz University Hospital, Neurology and Cerebrovascular Disease Group, Neuroscience Area of Hospital La Paz Institute for Health Research - IdiPAZ, Universidad Autónoma de Madrid,Madrid, Spain.
Pilar NozalDepartment of Immunology, La Paz University Hospital, Complement Research Group, of Hospital La Paz Institute for Health Research - IdiPAZ, Center for Biomedical Network Research on Rare Diseases (Ciberer), Madrid, Spain.
Juan Luis ChicoDepartment of Neurology, Ramon y Cajal University Hospital, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.
Antonio Tallón BarrancoNeuroimmunology and MS Unit, Department of Neurology, La Paz University Hospital, Neurology and Cerebrovascular Disease Group, Neuroscience Area of Hospital La Paz Institute for Health Research - IdiPAZ, Universidad Autónoma de Madrid,Madrid, Spain.
Laura Otero-OrtegaNeurology and Cerebrovascular Disease Group, Neuroscience Area of Hospital La Paz Institute for Health Research - IdiPAZ (La Paz University Hospital- Universidad Autónoma de Madrid), Madrid, Spain.
Iñigo CorralDepartment of Neurology, Ramon y Cajal University Hospital, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.
Angela CarrascoDepartment of Immunology, Ramon y Cajal University Hospital, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of Autoimmune Neurology is expanding rapidly, with new neural antibodies being identified each year. However, these disorders remain rare. Deciding when to test for these antibodies, when and what samples are to be obtained, how to handle and study them correctly, and how to interpret test results, is complex. In this article we review current diagnostic techniques and provide a comprehensive explanation on the study of these patients, in an effort to help with correct diagnosis minimizing false positive and false negative results. We also propose routine storage of samples and referral of certain cases to specialized research laboratories.

Indexed as

AntibodiesNeurologyHumansAntibodiesantibodiescell surface antigensintracellular antigenslaboratory techniquesneuroimmunology

Identifiers

PMID36569884
PMCPMC9768545

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.